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Antidepressant medication use and non-Hodgkin's lymphoma risk: no association.
Am J Epidemiol 2004; 160(6):566-75AJ

Abstract

Animal and human studies have suggested that antidepressant medications may be associated with several cancers. The authors evaluated the association between antidepressant medication use and the risk of non-Hodgkin's lymphoma using a Canadian population-based case-control study, the National Enhanced Cancer Surveillance Study. Non-Hodgkin's lymphoma cases (n=638) diagnosed in 1995-1996 were identified using the Ontario Cancer Registry, and controls (n=1,930) were identified from the Ontario Ministry of Finance Property Assessment Database. Antidepressant medication use was ascertained using a self-administered questionnaire. Multivariate logistic regression was used to estimate odds ratios. "Ever" use of antidepressant medications was not associated with non-Hodgkin's lymphoma risk. The odds ratio for non-Hodgkin's lymphoma with 25 or more months of tricyclic antidepressant medication use was 1.6; however, this was nonsignificant. Duration or history of use or individual types of antidepressant medications were not associated with non-Hodgkin's lymphoma risk. These findings do not support an increased risk of non-Hodgkin's lymphoma with antidepressant medication use.

Authors+Show Affiliations

Division of Preventive Oncology, Cancer Care Ontario, Toronto, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15353417

Citation

Bahl, Saira, et al. "Antidepressant Medication Use and non-Hodgkin's Lymphoma Risk: No Association." American Journal of Epidemiology, vol. 160, no. 6, 2004, pp. 566-75.
Bahl S, Cotterchio M, Kreiger N, et al. Antidepressant medication use and non-Hodgkin's lymphoma risk: no association. Am J Epidemiol. 2004;160(6):566-75.
Bahl, S., Cotterchio, M., Kreiger, N., & Klar, N. (2004). Antidepressant medication use and non-Hodgkin's lymphoma risk: no association. American Journal of Epidemiology, 160(6), pp. 566-75.
Bahl S, et al. Antidepressant Medication Use and non-Hodgkin's Lymphoma Risk: No Association. Am J Epidemiol. 2004 Sep 15;160(6):566-75. PubMed PMID: 15353417.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antidepressant medication use and non-Hodgkin's lymphoma risk: no association. AU - Bahl,Saira, AU - Cotterchio,Michelle, AU - Kreiger,Nancy, AU - Klar,Neil, PY - 2004/9/9/pubmed PY - 2004/10/8/medline PY - 2004/9/9/entrez SP - 566 EP - 75 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 160 IS - 6 N2 - Animal and human studies have suggested that antidepressant medications may be associated with several cancers. The authors evaluated the association between antidepressant medication use and the risk of non-Hodgkin's lymphoma using a Canadian population-based case-control study, the National Enhanced Cancer Surveillance Study. Non-Hodgkin's lymphoma cases (n=638) diagnosed in 1995-1996 were identified using the Ontario Cancer Registry, and controls (n=1,930) were identified from the Ontario Ministry of Finance Property Assessment Database. Antidepressant medication use was ascertained using a self-administered questionnaire. Multivariate logistic regression was used to estimate odds ratios. "Ever" use of antidepressant medications was not associated with non-Hodgkin's lymphoma risk. The odds ratio for non-Hodgkin's lymphoma with 25 or more months of tricyclic antidepressant medication use was 1.6; however, this was nonsignificant. Duration or history of use or individual types of antidepressant medications were not associated with non-Hodgkin's lymphoma risk. These findings do not support an increased risk of non-Hodgkin's lymphoma with antidepressant medication use. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/15353417/Antidepressant_medication_use_and_non_Hodgkin's_lymphoma_risk:_no_association_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwh234 DB - PRIME DP - Unbound Medicine ER -