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Antidepressant medication use and non-Hodgkin's lymphoma risk: no association.
Am J Epidemiol. 2004 Sep 15; 160(6):566-75.AJ

Abstract

Animal and human studies have suggested that antidepressant medications may be associated with several cancers. The authors evaluated the association between antidepressant medication use and the risk of non-Hodgkin's lymphoma using a Canadian population-based case-control study, the National Enhanced Cancer Surveillance Study. Non-Hodgkin's lymphoma cases (n=638) diagnosed in 1995-1996 were identified using the Ontario Cancer Registry, and controls (n=1,930) were identified from the Ontario Ministry of Finance Property Assessment Database. Antidepressant medication use was ascertained using a self-administered questionnaire. Multivariate logistic regression was used to estimate odds ratios. "Ever" use of antidepressant medications was not associated with non-Hodgkin's lymphoma risk. The odds ratio for non-Hodgkin's lymphoma with 25 or more months of tricyclic antidepressant medication use was 1.6; however, this was nonsignificant. Duration or history of use or individual types of antidepressant medications were not associated with non-Hodgkin's lymphoma risk. These findings do not support an increased risk of non-Hodgkin's lymphoma with antidepressant medication use.

Authors+Show Affiliations

Division of Preventive Oncology, Cancer Care Ontario, Toronto, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15353417

Citation

Bahl, Saira, et al. "Antidepressant Medication Use and non-Hodgkin's Lymphoma Risk: No Association." American Journal of Epidemiology, vol. 160, no. 6, 2004, pp. 566-75.
Bahl S, Cotterchio M, Kreiger N, et al. Antidepressant medication use and non-Hodgkin's lymphoma risk: no association. Am J Epidemiol. 2004;160(6):566-75.
Bahl, S., Cotterchio, M., Kreiger, N., & Klar, N. (2004). Antidepressant medication use and non-Hodgkin's lymphoma risk: no association. American Journal of Epidemiology, 160(6), 566-75.
Bahl S, et al. Antidepressant Medication Use and non-Hodgkin's Lymphoma Risk: No Association. Am J Epidemiol. 2004 Sep 15;160(6):566-75. PubMed PMID: 15353417.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antidepressant medication use and non-Hodgkin's lymphoma risk: no association. AU - Bahl,Saira, AU - Cotterchio,Michelle, AU - Kreiger,Nancy, AU - Klar,Neil, PY - 2004/9/9/pubmed PY - 2004/10/8/medline PY - 2004/9/9/entrez SP - 566 EP - 75 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 160 IS - 6 N2 - Animal and human studies have suggested that antidepressant medications may be associated with several cancers. The authors evaluated the association between antidepressant medication use and the risk of non-Hodgkin's lymphoma using a Canadian population-based case-control study, the National Enhanced Cancer Surveillance Study. Non-Hodgkin's lymphoma cases (n=638) diagnosed in 1995-1996 were identified using the Ontario Cancer Registry, and controls (n=1,930) were identified from the Ontario Ministry of Finance Property Assessment Database. Antidepressant medication use was ascertained using a self-administered questionnaire. Multivariate logistic regression was used to estimate odds ratios. "Ever" use of antidepressant medications was not associated with non-Hodgkin's lymphoma risk. The odds ratio for non-Hodgkin's lymphoma with 25 or more months of tricyclic antidepressant medication use was 1.6; however, this was nonsignificant. Duration or history of use or individual types of antidepressant medications were not associated with non-Hodgkin's lymphoma risk. These findings do not support an increased risk of non-Hodgkin's lymphoma with antidepressant medication use. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/15353417/Antidepressant_medication_use_and_non_Hodgkin's_lymphoma_risk:_no_association_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwh234 DB - PRIME DP - Unbound Medicine ER -