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Iron deficiency anemia after subtotal gastrectomy for gastric cancer.
Hepatogastroenterology. 2004 Sep-Oct; 51(59):1510-4.H

Abstract

BACKGROUND/AIMS

Sideropenic anemia after a gastrectomy is a frequent complication. The aim of the present study was to evaluate the role of different factors, such as sex, age, atrophic chronic gastritis, Helicobacter pylori infection and iron malabsorption, in iron deficiency after surgery for gastric cancer.

METHODOLOGY

Thirty-seven patients who underwent subtotal gastrectomy for carcinoma of the stomach were prospectively studied following a specific three-year protocol. Iron deficiency was evaluated by hemochromocytometric analysis and serum iron-ferritin level assays.

RESULTS

Of the different variables analyzed, atrophic chronic gastritis was associated with a lower mean serum iron level, in particular two years after surgery (65mg/dL vs. 103 mg/dL in subjects without gastritis, P<0.01); a correlation between Helicobacter pylori infection of the gastric stump and lower mean serum ferritin level was also found (25+/-6.3 mg/dL vs. 53+/-0.4 mg/dL, P<0.05). On the contrary, no association was observed with the other factors that were evaluated.

CONCLUSIONS

Among the factors involved in iron deficiency after gastrectomy for cancer of the stomach, atrophic gastritis seems to be the most important, although Helicobacter pylori infection of the gastric stump also seems to play an important role.

Authors+Show Affiliations

Roviello F
Department of Human Pathology and Oncology, Section of Surgical Oncology, University of Siena, Siena, Italy. roviello@unisi.it
Fotia G
No affiliation info available
Marrelli D
No affiliation info available
De Stefano A
No affiliation info available
Macchiarelli R
No affiliation info available
Pinto E
No affiliation info available

MeSH

AdenocarcinomaAdultAgedAged, 80 and overAnastomosis, SurgicalAnemia, Iron-DeficiencyChronic DiseaseFemaleFerritinsFollow-Up StudiesGastrectomyGastric StumpGastritis, AtrophicHelicobacter InfectionsHelicobacter pyloriHumansIronMaleMiddle AgedPostoperative ComplicationsProspective StudiesRisk FactorsStomach Neoplasms

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15362789

Citation

Roviello, Franco, et al. "Iron Deficiency Anemia After Subtotal Gastrectomy for Gastric Cancer." Hepato-gastroenterology, vol. 51, no. 59, 2004, pp. 1510-4.
Roviello F, Fotia G, Marrelli D, et al. Iron deficiency anemia after subtotal gastrectomy for gastric cancer. Hepatogastroenterology. 2004;51(59):1510-4.
Roviello, F., Fotia, G., Marrelli, D., De Stefano, A., Macchiarelli, R., & Pinto, E. (2004). Iron deficiency anemia after subtotal gastrectomy for gastric cancer. Hepato-gastroenterology, 51(59), 1510-4.
Roviello F, et al. Iron Deficiency Anemia After Subtotal Gastrectomy for Gastric Cancer. Hepatogastroenterology. 2004 Sep-Oct;51(59):1510-4. PubMed PMID: 15362789.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Iron deficiency anemia after subtotal gastrectomy for gastric cancer. AU - Roviello,Franco, AU - Fotia,Giuseppe, AU - Marrelli,Daniele, AU - De Stefano,Alfonso, AU - Macchiarelli,Raffaele, AU - Pinto,Enrico, PY - 2004/9/15/pubmed PY - 2004/10/13/medline PY - 2004/9/15/entrez SP - 1510 EP - 4 JF - Hepato-gastroenterology JO - Hepatogastroenterology VL - 51 IS - 59 N2 - BACKGROUND/AIMS: Sideropenic anemia after a gastrectomy is a frequent complication. The aim of the present study was to evaluate the role of different factors, such as sex, age, atrophic chronic gastritis, Helicobacter pylori infection and iron malabsorption, in iron deficiency after surgery for gastric cancer. METHODOLOGY: Thirty-seven patients who underwent subtotal gastrectomy for carcinoma of the stomach were prospectively studied following a specific three-year protocol. Iron deficiency was evaluated by hemochromocytometric analysis and serum iron-ferritin level assays. RESULTS: Of the different variables analyzed, atrophic chronic gastritis was associated with a lower mean serum iron level, in particular two years after surgery (65mg/dL vs. 103 mg/dL in subjects without gastritis, P<0.01); a correlation between Helicobacter pylori infection of the gastric stump and lower mean serum ferritin level was also found (25+/-6.3 mg/dL vs. 53+/-0.4 mg/dL, P<0.05). On the contrary, no association was observed with the other factors that were evaluated. CONCLUSIONS: Among the factors involved in iron deficiency after gastrectomy for cancer of the stomach, atrophic gastritis seems to be the most important, although Helicobacter pylori infection of the gastric stump also seems to play an important role. SN - 0172-6390 UR - https://www.unboundmedicine.com/medline/citation/15362789/Iron_deficiency_anemia_after_subtotal_gastrectomy_for_gastric_cancer_ L2 - https://www.diseaseinfosearch.org/result/3873 DB - PRIME DP - Unbound Medicine ER -