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Pulmonary thromboembolism in American Indians and Alaskan Natives.
Arch Intern Med. 2004 Sep 13; 164(16):1804-6.AI

Abstract

BACKGROUND

The rate of diagnosis of deep venous thrombosis and/or pulmonary embolism (collectively, venous thromboembolism: VTE) among patients discharged from Indian Health Service hospital care from 1980 through 1996 was considerably lower than rates reported in African Americans or whites. Expansion of the national census in 1990 to include American Indians and Alaskan Natives permits a more in-depth examination of this issue.

METHODS

Combined data from the National Hospital Discharge Survey (nonfederal hospitals) and the Indian Health Service (federal hospitals) from 1996 through 2001 were used to evaluate the rate of diagnosis of VTE in American Indians and Alaskan Natives.

RESULTS

The diagnosis of VTE in American Indians and Alaskan Natives, based on combined data from the National Hospital Discharge Survey and the Indian Health Service was 71 per 100,000 per year compared with 155 per 100,000 per year in African Americans (P<.001) and 131 per 100,000 per year in whites (P<.001). The rate ratio comparing the rate of diagnosis of VTE in American Indians and Alaskan Natives with African Americans was 0.46 (95% confidence interval, 0.45-0.47) and comparing American Indians and Alaskan Natives with whites it was 0.54 (95% confidence interval, 0.53-0.55).

CONCLUSIONS

The observed relatively low incidence of VTE in American Indians and Alaskan Natives would seem to be due to as yet undetermined genetic factors. The possibility that American Indians and Alaskan Natives have different lifestyles that affect the rate of diagnosis of VTE cannot be excluded.

Authors+Show Affiliations

Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, MI 48341-2985, USA. steinp@trinity-health.orgNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

15364676

Citation

Stein, Paul D., et al. "Pulmonary Thromboembolism in American Indians and Alaskan Natives." Archives of Internal Medicine, vol. 164, no. 16, 2004, pp. 1804-6.
Stein PD, Kayali F, Olson RE, et al. Pulmonary thromboembolism in American Indians and Alaskan Natives. Arch Intern Med. 2004;164(16):1804-6.
Stein, P. D., Kayali, F., Olson, R. E., & Milford, C. E. (2004). Pulmonary thromboembolism in American Indians and Alaskan Natives. Archives of Internal Medicine, 164(16), 1804-6.
Stein PD, et al. Pulmonary Thromboembolism in American Indians and Alaskan Natives. Arch Intern Med. 2004 Sep 13;164(16):1804-6. PubMed PMID: 15364676.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pulmonary thromboembolism in American Indians and Alaskan Natives. AU - Stein,Paul D, AU - Kayali,Fadi, AU - Olson,Ronald E, AU - Milford,Creagh E, PY - 2004/9/15/pubmed PY - 2005/2/16/medline PY - 2004/9/15/entrez SP - 1804 EP - 6 JF - Archives of internal medicine JO - Arch Intern Med VL - 164 IS - 16 N2 - BACKGROUND: The rate of diagnosis of deep venous thrombosis and/or pulmonary embolism (collectively, venous thromboembolism: VTE) among patients discharged from Indian Health Service hospital care from 1980 through 1996 was considerably lower than rates reported in African Americans or whites. Expansion of the national census in 1990 to include American Indians and Alaskan Natives permits a more in-depth examination of this issue. METHODS: Combined data from the National Hospital Discharge Survey (nonfederal hospitals) and the Indian Health Service (federal hospitals) from 1996 through 2001 were used to evaluate the rate of diagnosis of VTE in American Indians and Alaskan Natives. RESULTS: The diagnosis of VTE in American Indians and Alaskan Natives, based on combined data from the National Hospital Discharge Survey and the Indian Health Service was 71 per 100,000 per year compared with 155 per 100,000 per year in African Americans (P<.001) and 131 per 100,000 per year in whites (P<.001). The rate ratio comparing the rate of diagnosis of VTE in American Indians and Alaskan Natives with African Americans was 0.46 (95% confidence interval, 0.45-0.47) and comparing American Indians and Alaskan Natives with whites it was 0.54 (95% confidence interval, 0.53-0.55). CONCLUSIONS: The observed relatively low incidence of VTE in American Indians and Alaskan Natives would seem to be due to as yet undetermined genetic factors. The possibility that American Indians and Alaskan Natives have different lifestyles that affect the rate of diagnosis of VTE cannot be excluded. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/15364676/Pulmonary_thromboembolism_in_American_Indians_and_Alaskan_Natives_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/archinte.164.16.1804 DB - PRIME DP - Unbound Medicine ER -