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Exercise plus n-3 fatty acids: additive effect on postprandial lipemia.

Abstract

The purpose of this study was to examine changes in postprandial lipemia (PPL) in recreationally active males following aerobic exercise, omega-3 fatty acids (n-3FA) supplementation, and the combination of the two. PPL following a high-fat meal was measured in 10 recreationally active males (25 +/-1.5 years) under each of the following conditions: no exercise and no n-3 FA supplementation (control); exercise and no n-3FA supplementation (exercise); n-3FA supplementation and no exercise (n-3FA); and exercise and n-3 FA supplementation (combined). Blood was collected before the high-fat meal and at 2, 4, 6, and 8 hours after the meal to assess the PPL response. Supplementation consisted of 4.0 g of n-3FA per day for 5 weeks. Triglyceride (TG) peak response, the total area under the TG curve (TG-AUCT), and the incremental area under the TG curve (TG-AUCI) were used to define the PPL response. TG peak response was significantly reduced 38% by n-3FA supplementation and 50% by the combination of exercise and n-3FA supplementation. N-3FAs significantly reduced the TG-AUCT by 27% and by 42% when combined with exercise. When compared with the exercise trial, the TG-AUCT during the combined trial was significantly lower. Exercise, n-3FAs, and the combination significantly reduced the TG-AUCI by 40%, 42%, and 58%, respectively. These results suggest that the combination of exercise and n-3FA supplementation reduce PPL to a greater degree in recreationally active males when compared with the individual treatments.

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  • Authors+Show Affiliations

    ,

    Center for Physical Activity and Weight Management, Schiefelbusch Life Span Institute, University of Kansas, Lawrence, USA.

    , ,

    Source

    Metabolism: clinical and experimental 53:10 2004 Oct pg 1365-71

    MeSH

    Adult
    Area Under Curve
    Body Composition
    Cross-Over Studies
    Dietary Supplements
    Energy Intake
    Exercise
    Exercise Test
    Fatty Acids
    Fatty Acids, Omega-3
    Humans
    Lipids
    Lipoprotein Lipase
    Liver
    Male
    Oxygen Consumption
    Postprandial Period
    Triglycerides

    Pub Type(s)

    Clinical Trial
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    15375796

    Citation

    Smith, Bryan K., et al. "Exercise Plus N-3 Fatty Acids: Additive Effect On Postprandial Lipemia." Metabolism: Clinical and Experimental, vol. 53, no. 10, 2004, pp. 1365-71.
    Smith BK, Sun GY, Donahue OM, et al. Exercise plus n-3 fatty acids: additive effect on postprandial lipemia. Metab Clin Exp. 2004;53(10):1365-71.
    Smith, B. K., Sun, G. Y., Donahue, O. M., & Thomas, T. R. (2004). Exercise plus n-3 fatty acids: additive effect on postprandial lipemia. Metabolism: Clinical and Experimental, 53(10), pp. 1365-71.
    Smith BK, et al. Exercise Plus N-3 Fatty Acids: Additive Effect On Postprandial Lipemia. Metab Clin Exp. 2004;53(10):1365-71. PubMed PMID: 15375796.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Exercise plus n-3 fatty acids: additive effect on postprandial lipemia. AU - Smith,Bryan K, AU - Sun,Grace Y, AU - Donahue,Owen M, AU - Thomas,Tom R, PY - 2004/9/18/pubmed PY - 2004/11/13/medline PY - 2004/9/18/entrez SP - 1365 EP - 71 JF - Metabolism: clinical and experimental JO - Metab. Clin. Exp. VL - 53 IS - 10 N2 - The purpose of this study was to examine changes in postprandial lipemia (PPL) in recreationally active males following aerobic exercise, omega-3 fatty acids (n-3FA) supplementation, and the combination of the two. PPL following a high-fat meal was measured in 10 recreationally active males (25 +/-1.5 years) under each of the following conditions: no exercise and no n-3 FA supplementation (control); exercise and no n-3FA supplementation (exercise); n-3FA supplementation and no exercise (n-3FA); and exercise and n-3 FA supplementation (combined). Blood was collected before the high-fat meal and at 2, 4, 6, and 8 hours after the meal to assess the PPL response. Supplementation consisted of 4.0 g of n-3FA per day for 5 weeks. Triglyceride (TG) peak response, the total area under the TG curve (TG-AUCT), and the incremental area under the TG curve (TG-AUCI) were used to define the PPL response. TG peak response was significantly reduced 38% by n-3FA supplementation and 50% by the combination of exercise and n-3FA supplementation. N-3FAs significantly reduced the TG-AUCT by 27% and by 42% when combined with exercise. When compared with the exercise trial, the TG-AUCT during the combined trial was significantly lower. Exercise, n-3FAs, and the combination significantly reduced the TG-AUCI by 40%, 42%, and 58%, respectively. These results suggest that the combination of exercise and n-3FA supplementation reduce PPL to a greater degree in recreationally active males when compared with the individual treatments. SN - 0026-0495 UR - https://www.unboundmedicine.com/medline/citation/15375796/Exercise_plus_n_3_fatty_acids:_additive_effect_on_postprandial_lipemia_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0026049504002434 DB - PRIME DP - Unbound Medicine ER -