Tags

Type your tag names separated by a space and hit enter

Immunomodulating and anti-tumor action of extracts of several mushrooms.
J Biotechnol. 2004 Sep 30; 113(1-3):77-83.JB

Abstract

Aqueous extracts from fruit bodies and mycelia of various higher Basidiomycetes were studied in search for reliable biological effects. In vitro and in vivo experiments were conducted. The results showed that the aqueous extracts demonstrated various types of marked biological actions: an increased production of reactive oxygen forms by neutrophil cells of human peripheral blood; a significant mitogenic activity in a wide range of concentrations; stimulation on production of inflammatory cytokines interleukine 1-beta and interleukine-8 by peripheral blood cells; a decrease in both average tumor size in mice with transplanted melanoma B16 and a manifestation of tumorous intoxication; and a prolongation in the survival rate of such mice.

Authors+Show Affiliations

Shamtsyan M
Department of Technology of Microbiological Synthesis, St. Petersburg State Institute of Technology (Technical University), 26 Moscovsky Pr., 198013, Russia. shamtsyan@yahoo.com
Konusova V
No affiliation info available
Maksimova Y
No affiliation info available
Goloshchev A
No affiliation info available
Panchenko A
No affiliation info available
Simbirtsev A
No affiliation info available
Petrishchev N
No affiliation info available
Denisova N
No affiliation info available

MeSH

Adjuvants, ImmunologicAgaricalesAnimalsAntineoplastic AgentsHumansMelanomaMiceMice, Inbred CBANeoplasm TransplantationNeutrophilsReactive Oxygen SpeciesSkin Neoplasms

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15380649

Citation

Shamtsyan, Mark, et al. "Immunomodulating and Anti-tumor Action of Extracts of Several Mushrooms." Journal of Biotechnology, vol. 113, no. 1-3, 2004, pp. 77-83.
Shamtsyan M, Konusova V, Maksimova Y, et al. Immunomodulating and anti-tumor action of extracts of several mushrooms. J Biotechnol. 2004;113(1-3):77-83.
Shamtsyan, M., Konusova, V., Maksimova, Y., Goloshchev, A., Panchenko, A., Simbirtsev, A., Petrishchev, N., & Denisova, N. (2004). Immunomodulating and anti-tumor action of extracts of several mushrooms. Journal of Biotechnology, 113(1-3), 77-83.
Shamtsyan M, et al. Immunomodulating and Anti-tumor Action of Extracts of Several Mushrooms. J Biotechnol. 2004 Sep 30;113(1-3):77-83. PubMed PMID: 15380649.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immunomodulating and anti-tumor action of extracts of several mushrooms. AU - Shamtsyan,Mark, AU - Konusova,Valentina, AU - Maksimova,Yulia, AU - Goloshchev,Alexander, AU - Panchenko,Andrey, AU - Simbirtsev,Andrey, AU - Petrishchev,Nikolay, AU - Denisova,Nina, PY - 2003/08/29/received PY - 2004/03/23/revised PY - 2004/04/01/accepted PY - 2004/9/24/pubmed PY - 2004/11/9/medline PY - 2004/9/24/entrez SP - 77 EP - 83 JF - Journal of biotechnology JO - J Biotechnol VL - 113 IS - 1-3 N2 - Aqueous extracts from fruit bodies and mycelia of various higher Basidiomycetes were studied in search for reliable biological effects. In vitro and in vivo experiments were conducted. The results showed that the aqueous extracts demonstrated various types of marked biological actions: an increased production of reactive oxygen forms by neutrophil cells of human peripheral blood; a significant mitogenic activity in a wide range of concentrations; stimulation on production of inflammatory cytokines interleukine 1-beta and interleukine-8 by peripheral blood cells; a decrease in both average tumor size in mice with transplanted melanoma B16 and a manifestation of tumorous intoxication; and a prolongation in the survival rate of such mice. SN - 0168-1656 UR - https://www.unboundmedicine.com/medline/citation/15380649/Immunomodulating_and_anti_tumor_action_of_extracts_of_several_mushrooms_ DB - PRIME DP - Unbound Medicine ER -