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Organ allocation for liver-intestine candidates.
Liver Transpl. 2004 Oct; 10(10 Suppl 2):S86-9.LT

Abstract

1. Patients listed for combined liver and intestine transplantation have the highest waitlist mortality of any transplant candidates. 2. Liver-intestine candidates have higher mortality rates than other patients listed for liver transplantation at all model for end-stage liver disease (MELD) and pediatric end-stage liver disease (PELD) scores, sepsis rather than liver failure being the major cause of death in this group. 3. Increasing PELD scores appear to correlate with increasing waitlist mortality in patients awaiting combined liver and intestinal transplantation. 4. Present policy to increase MELD / PELD scores for liver-intestine patients by an additional estimated 10% mortality risk is an attempt to bridge the difference in waitlist mortality while maintaining the principle of allocating organs on the basis of disease severity. 5. Scheduled reevaluation of present allocation practices is essential to refine Organ Procurement and Transplantation Network United Network for Organ Sharing policy as it relates to patients in need of combined liver and intestinal transplantation.

Authors+Show Affiliations

Section of Pediatric Gastroenterology & Nutrition, University of Nebraska Medical Center, Omaha, NE, USA. shorslen@surgery.unmc.edu

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15382223

Citation

Horslen, Simon. "Organ Allocation for Liver-intestine Candidates." Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, vol. 10, no. 10 Suppl 2, 2004, pp. S86-9.
Horslen S. Organ allocation for liver-intestine candidates. Liver Transpl. 2004;10(10 Suppl 2):S86-9.
Horslen, S. (2004). Organ allocation for liver-intestine candidates. Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 10(10 Suppl 2), S86-9.
Horslen S. Organ Allocation for Liver-intestine Candidates. Liver Transpl. 2004;10(10 Suppl 2):S86-9. PubMed PMID: 15382223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Organ allocation for liver-intestine candidates. A1 - Horslen,Simon, PY - 2004/9/24/pubmed PY - 2005/2/11/medline PY - 2004/9/24/entrez SP - S86 EP - 9 JF - Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society JO - Liver Transpl VL - 10 IS - 10 Suppl 2 N2 - 1. Patients listed for combined liver and intestine transplantation have the highest waitlist mortality of any transplant candidates. 2. Liver-intestine candidates have higher mortality rates than other patients listed for liver transplantation at all model for end-stage liver disease (MELD) and pediatric end-stage liver disease (PELD) scores, sepsis rather than liver failure being the major cause of death in this group. 3. Increasing PELD scores appear to correlate with increasing waitlist mortality in patients awaiting combined liver and intestinal transplantation. 4. Present policy to increase MELD / PELD scores for liver-intestine patients by an additional estimated 10% mortality risk is an attempt to bridge the difference in waitlist mortality while maintaining the principle of allocating organs on the basis of disease severity. 5. Scheduled reevaluation of present allocation practices is essential to refine Organ Procurement and Transplantation Network United Network for Organ Sharing policy as it relates to patients in need of combined liver and intestinal transplantation. SN - 1527-6465 UR - https://www.unboundmedicine.com/medline/citation/15382223/Organ_allocation_for_liver_intestine_candidates_ L2 - https://doi.org/10.1002/lt.20257 DB - PRIME DP - Unbound Medicine ER -