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Pregnancy-associated severe liver dysfunction.
Crit Care Clin. 2004 Oct; 20(4):763-76, xi.CC

Abstract

Determining the cause of liver disease in pregnancy can present a difficult challenge for clinicians. Minor elevations in aminotransferases may be a harbinger of life-threatening processes, such as acute fatty liver of pregnancy (AFLP) or hemolysis, elevated liver enzyme levels, low platelet count (HELLP) syndrome. Preeclampsia, HELLP syndrome, and AFLP form a spectrum of disease that ranges from involving mild symptoms to severe life-threatening multiorgan system dysfunction. They have been shown to be the primary causes of severe hepatic dysfunction during pregnancy. This article attempts to define the clinical and diagnostic features, pathophysiology, and treatment options of these diseases.

Authors+Show Affiliations

Department of Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA. jay.steingrub@bhs.org

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15388201

Citation

Steingrub, Jay S.. "Pregnancy-associated Severe Liver Dysfunction." Critical Care Clinics, vol. 20, no. 4, 2004, pp. 763-76, xi.
Steingrub JS. Pregnancy-associated severe liver dysfunction. Crit Care Clin. 2004;20(4):763-76, xi.
Steingrub, J. S. (2004). Pregnancy-associated severe liver dysfunction. Critical Care Clinics, 20(4), 763-76, xi.
Steingrub JS. Pregnancy-associated Severe Liver Dysfunction. Crit Care Clin. 2004;20(4):763-76, xi. PubMed PMID: 15388201.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pregnancy-associated severe liver dysfunction. A1 - Steingrub,Jay S, PY - 2004/9/25/pubmed PY - 2004/11/17/medline PY - 2004/9/25/entrez SP - 763-76, xi JF - Critical care clinics JO - Crit Care Clin VL - 20 IS - 4 N2 - Determining the cause of liver disease in pregnancy can present a difficult challenge for clinicians. Minor elevations in aminotransferases may be a harbinger of life-threatening processes, such as acute fatty liver of pregnancy (AFLP) or hemolysis, elevated liver enzyme levels, low platelet count (HELLP) syndrome. Preeclampsia, HELLP syndrome, and AFLP form a spectrum of disease that ranges from involving mild symptoms to severe life-threatening multiorgan system dysfunction. They have been shown to be the primary causes of severe hepatic dysfunction during pregnancy. This article attempts to define the clinical and diagnostic features, pathophysiology, and treatment options of these diseases. SN - 0749-0704 UR - https://www.unboundmedicine.com/medline/citation/15388201/Pregnancy_associated_severe_liver_dysfunction_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0749-0704(04)00051-X DB - PRIME DP - Unbound Medicine ER -