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Reduction of urinary oxalate by combined calcium and citrate administration without increase in urinary calcium oxalate stone formers.
Clin Nephrol. 1992 Jan; 37(1):14-8.CN

Abstract

Oxalic acid seems to play a far greater role in the formation of calcium oxalate stone than calcium. Three grams of calcium lactate and 3 g of sodium potassium citrate were administered to 46 urolithiasis patients, whose stones were mainly composed of calcium oxalate. Urinary oxalate level was reduced significantly without raising urinary calcium level by the administration of the two drugs for two weeks. The reduction of urinary oxalic acid was particularly remarkable in patients without hypercalciuria. The mechanism of action of these drugs was discussed.

Authors+Show Affiliations

Ito H
Department of Urology, Teikyo University School of Medicine, Ichihara Hospital, Japan.
Suzuki F
No affiliation info available
Yamaguchi K
No affiliation info available
Nishikawa Y
No affiliation info available
Kotake T
No affiliation info available

MeSH

AdultAgedCalciumCalcium, DietaryCitratesCitric AcidCreatinineDrug CombinationsFemaleHumansKidney CalculiMagnesiumMaleMiddle AgedOxalatesOxalic AcidPhosphorus

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1541059

Citation

Ito, H, et al. "Reduction of Urinary Oxalate By Combined Calcium and Citrate Administration Without Increase in Urinary Calcium Oxalate Stone Formers." Clinical Nephrology, vol. 37, no. 1, 1992, pp. 14-8.
Ito H, Suzuki F, Yamaguchi K, et al. Reduction of urinary oxalate by combined calcium and citrate administration without increase in urinary calcium oxalate stone formers. Clin Nephrol. 1992;37(1):14-8.
Ito, H., Suzuki, F., Yamaguchi, K., Nishikawa, Y., & Kotake, T. (1992). Reduction of urinary oxalate by combined calcium and citrate administration without increase in urinary calcium oxalate stone formers. Clinical Nephrology, 37(1), 14-8.
Ito H, et al. Reduction of Urinary Oxalate By Combined Calcium and Citrate Administration Without Increase in Urinary Calcium Oxalate Stone Formers. Clin Nephrol. 1992;37(1):14-8. PubMed PMID: 1541059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reduction of urinary oxalate by combined calcium and citrate administration without increase in urinary calcium oxalate stone formers. AU - Ito,H, AU - Suzuki,F, AU - Yamaguchi,K, AU - Nishikawa,Y, AU - Kotake,T, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 14 EP - 8 JF - Clinical nephrology JO - Clin Nephrol VL - 37 IS - 1 N2 - Oxalic acid seems to play a far greater role in the formation of calcium oxalate stone than calcium. Three grams of calcium lactate and 3 g of sodium potassium citrate were administered to 46 urolithiasis patients, whose stones were mainly composed of calcium oxalate. Urinary oxalate level was reduced significantly without raising urinary calcium level by the administration of the two drugs for two weeks. The reduction of urinary oxalic acid was particularly remarkable in patients without hypercalciuria. The mechanism of action of these drugs was discussed. SN - 0301-0430 UR - https://www.unboundmedicine.com/medline/citation/1541059/Reduction_of_urinary_oxalate_by_combined_calcium_and_citrate_administration_without_increase_in_urinary_calcium_oxalate_stone_formers_ DB - PRIME DP - Unbound Medicine ER -