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Dietary patterns associated with colon and rectal cancer: results from the Dietary Patterns and Cancer (DIETSCAN) Project.
Am J Clin Nutr. 2004 Oct; 80(4):1003-11.AJ

Abstract

BACKGROUND

An analysis of dietary patterns or combinations of foods may provide insight regarding the influence of diet on the risk of colon and rectal cancer.

OBJECTIVE

A primary aim of the Dietary Patterns and Cancer (DIETSCAN) Project was to develop and apply a common methodologic approach to study dietary patterns and cancer in 4 European cohorts: the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study (Finland-ATBC), the Netherlands Cohort Study (NLCS) on Diet and Cancer, the Swedish Mammography Cohort (SMC), and the Ormoni e Dieta nella Eziologia dei Tumori (Italy-ORDET). Three cohorts (ATBC, NLCS, and SMC) provided data on colon and rectal cancer for the present study.

DESIGN

The cohorts were established between 1985 and 1992; follow-up data were obtained from national cancer registries. The participants completed validated semiquantitative food-frequency questionnaires at baseline.

RESULTS

Exploratory factor analysis, conducted within each cohort, identified 3-5 stable dietary patterns. Two dietary patterns-Vegetables and Pork, Processed Meats, Potatoes (PPP)-were common across all cohorts. After adjustment for potential confounders, PPP was associated with an increased risk of colon cancer in the SMC women (quintile 4(multivariate) relative risk: 1.62; 95% CI: 1.12, 2.34; P for trend = 0.01). PPP was also associated with an increased risk of rectal cancer in the ATBC men (quintile 4(multivariate) relative risk: 2.21; 95% CI: 1.07, 4.57; P for trend = 0.05). Neither pattern was associated with the risk of colon or rectal cancer in the NLCS women and men.

CONCLUSION

Although certain dietary patterns may be consistent across European countries, associations between these dietary patterns and the risk of colon and rectal cancer are not conclusive.

Authors+Show Affiliations

New York University, Department of Nutrition, Food Studies, and Public Health, New York, NY, USA. beth.dixon@nyu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15447912

Citation

Dixon, L Beth, et al. "Dietary Patterns Associated With Colon and Rectal Cancer: Results From the Dietary Patterns and Cancer (DIETSCAN) Project." The American Journal of Clinical Nutrition, vol. 80, no. 4, 2004, pp. 1003-11.
Dixon LB, Balder HF, Virtanen MJ, et al. Dietary patterns associated with colon and rectal cancer: results from the Dietary Patterns and Cancer (DIETSCAN) Project. Am J Clin Nutr. 2004;80(4):1003-11.
Dixon, L. B., Balder, H. F., Virtanen, M. J., Rashidkhani, B., Männistö, S., Krogh, V., van Den Brandt, P. A., Hartman, A. M., Pietinen, P., Tan, F., Virtamo, J., Wolk, A., & Goldbohm, R. A. (2004). Dietary patterns associated with colon and rectal cancer: results from the Dietary Patterns and Cancer (DIETSCAN) Project. The American Journal of Clinical Nutrition, 80(4), 1003-11.
Dixon LB, et al. Dietary Patterns Associated With Colon and Rectal Cancer: Results From the Dietary Patterns and Cancer (DIETSCAN) Project. Am J Clin Nutr. 2004;80(4):1003-11. PubMed PMID: 15447912.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary patterns associated with colon and rectal cancer: results from the Dietary Patterns and Cancer (DIETSCAN) Project. AU - Dixon,L Beth, AU - Balder,Helena F, AU - Virtanen,Mikko J, AU - Rashidkhani,Bahram, AU - Männistö,Satu, AU - Krogh,Vittorio, AU - van Den Brandt,Piet A, AU - Hartman,Anne M, AU - Pietinen,Pirjo, AU - Tan,Frans, AU - Virtamo,Jarmo, AU - Wolk,Alicja, AU - Goldbohm,R Alexandra, PY - 2004/9/28/pubmed PY - 2004/10/20/medline PY - 2004/9/28/entrez SP - 1003 EP - 11 JF - The American journal of clinical nutrition JO - Am J Clin Nutr VL - 80 IS - 4 N2 - BACKGROUND: An analysis of dietary patterns or combinations of foods may provide insight regarding the influence of diet on the risk of colon and rectal cancer. OBJECTIVE: A primary aim of the Dietary Patterns and Cancer (DIETSCAN) Project was to develop and apply a common methodologic approach to study dietary patterns and cancer in 4 European cohorts: the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study (Finland-ATBC), the Netherlands Cohort Study (NLCS) on Diet and Cancer, the Swedish Mammography Cohort (SMC), and the Ormoni e Dieta nella Eziologia dei Tumori (Italy-ORDET). Three cohorts (ATBC, NLCS, and SMC) provided data on colon and rectal cancer for the present study. DESIGN: The cohorts were established between 1985 and 1992; follow-up data were obtained from national cancer registries. The participants completed validated semiquantitative food-frequency questionnaires at baseline. RESULTS: Exploratory factor analysis, conducted within each cohort, identified 3-5 stable dietary patterns. Two dietary patterns-Vegetables and Pork, Processed Meats, Potatoes (PPP)-were common across all cohorts. After adjustment for potential confounders, PPP was associated with an increased risk of colon cancer in the SMC women (quintile 4(multivariate) relative risk: 1.62; 95% CI: 1.12, 2.34; P for trend = 0.01). PPP was also associated with an increased risk of rectal cancer in the ATBC men (quintile 4(multivariate) relative risk: 2.21; 95% CI: 1.07, 4.57; P for trend = 0.05). Neither pattern was associated with the risk of colon or rectal cancer in the NLCS women and men. CONCLUSION: Although certain dietary patterns may be consistent across European countries, associations between these dietary patterns and the risk of colon and rectal cancer are not conclusive. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/15447912/Dietary_patterns_associated_with_colon_and_rectal_cancer:_results_from_the_Dietary_Patterns_and_Cancer__DIETSCAN__Project_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/80.4.1003 DB - PRIME DP - Unbound Medicine ER -