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Substance use and posttraumatic stress disorders: symptom interplay and effects on outcome.
Addict Behav. 2004 Nov; 29(8):1665-72.AB

Abstract

This study examined concurrent and prospective associations between substance use disorder (SUD) and posttraumatic stress disorder (PTSD) diagnosis and symptoms and mechanisms underlying these associations. Participants (n = 133) were assessed at intake and 6 months following inpatient SUD treatment. Patients differed by baseline PTSD status on psychiatric comorbidity and substance use history but not on current substance use symptoms. Participants with alcohol use disorders reported a greater number of reexperiencing symptoms. Baseline PTSD status did not predict substance use outcome. However, change in PTSD status over follow-up predicted substance use outcomes; those with unremitted PTSD demonstrated poorer SUD outcome than those with remitted PTSD. General psychiatric distress at follow-up was associated with poorer outcomes, and such distress mediated the association between PTSD change status and substance use outcome. Findings suggest that clinicians should assess for PTSD among those with SUD and, during treatment, should monitor PTSD and other psychological symptoms, which may be risk factors for relapse to substance abuse.

Authors+Show Affiliations

Read JP
State University of New York at Buffalo, 14260, USA. JPRead@Buffalo.edu
Brown PJ
No affiliation info available
Kahler CW
No affiliation info available

MeSH

AdolescentAdultDiagnosis, Dual (Psychiatry)FemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisPsychiatric Status Rating ScalesRemission InductionStress Disorders, Post-TraumaticSubstance-Related DisordersTreatment Outcome

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15451135

Citation

Read, Jennifer P., et al. "Substance Use and Posttraumatic Stress Disorders: Symptom Interplay and Effects On Outcome." Addictive Behaviors, vol. 29, no. 8, 2004, pp. 1665-72.
Read JP, Brown PJ, Kahler CW. Substance use and posttraumatic stress disorders: symptom interplay and effects on outcome. Addict Behav. 2004;29(8):1665-72.
Read, J. P., Brown, P. J., & Kahler, C. W. (2004). Substance use and posttraumatic stress disorders: symptom interplay and effects on outcome. Addictive Behaviors, 29(8), 1665-72.
Read JP, Brown PJ, Kahler CW. Substance Use and Posttraumatic Stress Disorders: Symptom Interplay and Effects On Outcome. Addict Behav. 2004;29(8):1665-72. PubMed PMID: 15451135.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Substance use and posttraumatic stress disorders: symptom interplay and effects on outcome. AU - Read,Jennifer P, AU - Brown,Pamela J, AU - Kahler,Christopher W, PY - 2004/9/29/pubmed PY - 2004/12/28/medline PY - 2004/9/29/entrez SP - 1665 EP - 72 JF - Addictive behaviors JO - Addict Behav VL - 29 IS - 8 N2 - This study examined concurrent and prospective associations between substance use disorder (SUD) and posttraumatic stress disorder (PTSD) diagnosis and symptoms and mechanisms underlying these associations. Participants (n = 133) were assessed at intake and 6 months following inpatient SUD treatment. Patients differed by baseline PTSD status on psychiatric comorbidity and substance use history but not on current substance use symptoms. Participants with alcohol use disorders reported a greater number of reexperiencing symptoms. Baseline PTSD status did not predict substance use outcome. However, change in PTSD status over follow-up predicted substance use outcomes; those with unremitted PTSD demonstrated poorer SUD outcome than those with remitted PTSD. General psychiatric distress at follow-up was associated with poorer outcomes, and such distress mediated the association between PTSD change status and substance use outcome. Findings suggest that clinicians should assess for PTSD among those with SUD and, during treatment, should monitor PTSD and other psychological symptoms, which may be risk factors for relapse to substance abuse. SN - 0306-4603 UR - https://www.unboundmedicine.com/medline/citation/15451135/Substance_use_and_posttraumatic_stress_disorders:_symptom_interplay_and_effects_on_outcome_ DB - PRIME DP - Unbound Medicine ER -