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Sclerosing lobular hyperplasia of the breast: fine-needle aspiration cytology findings--a case report.
Diagn Cytopathol. 2004 Nov; 31(5):340-1.DC

Abstract

Sclerosing lobular hyperplasia (SLH) is an uncommon benign lesion seen in the juvenile breast. It presents as a palpable, firm, circumscribed nodular lump in the breast of a young woman. Histologically, it is characterised by prominent lobular hyperplasia and sclerosis of the intralobular connective tissue. We discuss the cytomorphology and differential diagnosis. A 16-yr-old female patient presented with a painless, firm, nodular, mobile mass in the right breast measuring 4 x 4 cm. The clinical and radiological diagnosis was fibroadenoma. Fine-needle aspiration smears showed round to oval ductal epithelial cells in flat sheets and round clusters with an acinar arrangement. A few bare nuclei were seen dispersed in a clean background but no stroma was visualised. A combination of clinical findings, imaging, and cytological features of SLH can help to differentiate this condition from other palpable juvenile breast diseases.

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Authors+Show Affiliations

Panikar N
Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Shahdara, Delhi, India.
Agarwal S
No affiliation info available

MeSH

AdolescentBiopsy, Fine-NeedleBreastBreast DiseasesBreast NeoplasmsDiagnosis, DifferentialFemaleFibroadenomaHumansHyperplasiaSclerosisTreatment Outcome

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

15468127

Citation

Panikar, Nirupma, and Sarla Agarwal. "Sclerosing Lobular Hyperplasia of the Breast: Fine-needle Aspiration Cytology Findings--a Case Report." Diagnostic Cytopathology, vol. 31, no. 5, 2004, pp. 340-1.
Panikar N, Agarwal S. Sclerosing lobular hyperplasia of the breast: fine-needle aspiration cytology findings--a case report. Diagn Cytopathol. 2004;31(5):340-1.
Panikar, N., & Agarwal, S. (2004). Sclerosing lobular hyperplasia of the breast: fine-needle aspiration cytology findings--a case report. Diagnostic Cytopathology, 31(5), 340-1.
Panikar N, Agarwal S. Sclerosing Lobular Hyperplasia of the Breast: Fine-needle Aspiration Cytology Findings--a Case Report. Diagn Cytopathol. 2004;31(5):340-1. PubMed PMID: 15468127.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sclerosing lobular hyperplasia of the breast: fine-needle aspiration cytology findings--a case report. AU - Panikar,Nirupma, AU - Agarwal,Sarla, PY - 2004/10/7/pubmed PY - 2005/3/9/medline PY - 2004/10/7/entrez SP - 340 EP - 1 JF - Diagnostic cytopathology JO - Diagn Cytopathol VL - 31 IS - 5 N2 - Sclerosing lobular hyperplasia (SLH) is an uncommon benign lesion seen in the juvenile breast. It presents as a palpable, firm, circumscribed nodular lump in the breast of a young woman. Histologically, it is characterised by prominent lobular hyperplasia and sclerosis of the intralobular connective tissue. We discuss the cytomorphology and differential diagnosis. A 16-yr-old female patient presented with a painless, firm, nodular, mobile mass in the right breast measuring 4 x 4 cm. The clinical and radiological diagnosis was fibroadenoma. Fine-needle aspiration smears showed round to oval ductal epithelial cells in flat sheets and round clusters with an acinar arrangement. A few bare nuclei were seen dispersed in a clean background but no stroma was visualised. A combination of clinical findings, imaging, and cytological features of SLH can help to differentiate this condition from other palpable juvenile breast diseases. SN - 8755-1039 UR - https://www.unboundmedicine.com/medline/citation/15468127/Sclerosing_lobular_hyperplasia_of_the_breast:_fine_needle_aspiration_cytology_findings__a_case_report_ L2 - https://doi.org/10.1002/dc.20135 DB - PRIME DP - Unbound Medicine ER -