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Outcomes of hospitalizations for myocardial infarctions and cerebrovascular accidents in patients with systemic lupus erythematosus.
Arthritis Rheum 2004; 50(10):3170-6AR

Abstract

OBJECTIVE

Patients with systemic lupus erythematosus (SLE) have increased risks of acute myocardial infarction (AMI) and cerebrovascular accident (CVA), but it is not known whether they have worse outcomes after AMI or CVA compared with patients without SLE. This study compared in-hospital mortality, length of stay, and other measures of severity (congestive heart failure or need for coronary artery bypass grafting after AMI; discharge to a skilled nursing facility after CVA) between patients with SLE and patients without SLE who were hospitalized for AMI or CVA.

METHODS

Data on all patients hospitalized in California with either AMI or CVA from 1996 to 2000 were abstracted from a state hospitalization database. Outcomes after AMI were compared between 519 patients with SLE and 214,771 patients without SLE, and outcomes after CVA were compared between 905 patients with SLE and 293,326 patients without SLE. Analyses were performed separately for men and women.

RESULTS

Among women with AMI, there were no differences in the risk of in-hospital mortality, long length of stay, or congestive heart failure between patients with SLE and those without SLE, but women with SLE were less likely to undergo coronary artery bypass grafting. Outcomes after AMI did not differ between men with SLE and men without SLE. Among women with CVA, there were no differences in outcomes between patients with SLE and patients without SLE. Men with SLE were almost twice as likely to have a long length of stay after CVA than were men without SLE.

CONCLUSION

Outcomes after AMI and CVA are generally similar between patients with SLE and those without SLE.

Authors+Show Affiliations

National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland, USA20892-1828. wardm1@mail.nih.gov

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

15476215

Citation

Ward, Michael M.. "Outcomes of Hospitalizations for Myocardial Infarctions and Cerebrovascular Accidents in Patients With Systemic Lupus Erythematosus." Arthritis and Rheumatism, vol. 50, no. 10, 2004, pp. 3170-6.
Ward MM. Outcomes of hospitalizations for myocardial infarctions and cerebrovascular accidents in patients with systemic lupus erythematosus. Arthritis Rheum. 2004;50(10):3170-6.
Ward, M. M. (2004). Outcomes of hospitalizations for myocardial infarctions and cerebrovascular accidents in patients with systemic lupus erythematosus. Arthritis and Rheumatism, 50(10), pp. 3170-6.
Ward MM. Outcomes of Hospitalizations for Myocardial Infarctions and Cerebrovascular Accidents in Patients With Systemic Lupus Erythematosus. Arthritis Rheum. 2004;50(10):3170-6. PubMed PMID: 15476215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcomes of hospitalizations for myocardial infarctions and cerebrovascular accidents in patients with systemic lupus erythematosus. A1 - Ward,Michael M, PY - 2004/10/12/pubmed PY - 2004/12/16/medline PY - 2004/10/12/entrez SP - 3170 EP - 6 JF - Arthritis and rheumatism JO - Arthritis Rheum. VL - 50 IS - 10 N2 - OBJECTIVE: Patients with systemic lupus erythematosus (SLE) have increased risks of acute myocardial infarction (AMI) and cerebrovascular accident (CVA), but it is not known whether they have worse outcomes after AMI or CVA compared with patients without SLE. This study compared in-hospital mortality, length of stay, and other measures of severity (congestive heart failure or need for coronary artery bypass grafting after AMI; discharge to a skilled nursing facility after CVA) between patients with SLE and patients without SLE who were hospitalized for AMI or CVA. METHODS: Data on all patients hospitalized in California with either AMI or CVA from 1996 to 2000 were abstracted from a state hospitalization database. Outcomes after AMI were compared between 519 patients with SLE and 214,771 patients without SLE, and outcomes after CVA were compared between 905 patients with SLE and 293,326 patients without SLE. Analyses were performed separately for men and women. RESULTS: Among women with AMI, there were no differences in the risk of in-hospital mortality, long length of stay, or congestive heart failure between patients with SLE and those without SLE, but women with SLE were less likely to undergo coronary artery bypass grafting. Outcomes after AMI did not differ between men with SLE and men without SLE. Among women with CVA, there were no differences in outcomes between patients with SLE and patients without SLE. Men with SLE were almost twice as likely to have a long length of stay after CVA than were men without SLE. CONCLUSION: Outcomes after AMI and CVA are generally similar between patients with SLE and those without SLE. SN - 0004-3591 UR - https://www.unboundmedicine.com/medline/citation/15476215/Outcomes_of_hospitalizations_for_myocardial_infarctions_and_cerebrovascular_accidents_in_patients_with_systemic_lupus_erythematosus_ L2 - https://doi.org/10.1002/art.20556 DB - PRIME DP - Unbound Medicine ER -