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Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes.
Ann Med 2004; 36(5):355-66AM

Abstract

The risk of cardiovascular disease is markedly increased in patients with type 2 diabetes with a prevalence twice as high compared to the background population. With the recognition of multiple concomitant risk factors for both microvascular as well as cardiovascular disease in type 2 diabetic patients, treatment strategies have changed during recent years. This review focuses on the many recent drug trials that have set the course for an effective multifactorial treatment of the disease. Thus, the Steno-2 Study has shown that an intensified multifactorial intervention targeting several risk factors for cardiovascular disease is capable of reducing the risk for a combined endpoint of cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, coronary interventions, revascularisation to legs, and amputations by 50%.

Authors+Show Affiliations

Steno Diabetes Center, Niels Steensensvej 2, 2820 Gentofte, Copenhagen, Denmark.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15478310

Citation

Gaede, Peter, and Oluf Pedersen. "Target Intervention Against Multiple-risk Markers to Reduce Cardiovascular Disease in Patients With Type 2 Diabetes." Annals of Medicine, vol. 36, no. 5, 2004, pp. 355-66.
Gaede P, Pedersen O. Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes. Ann Med. 2004;36(5):355-66.
Gaede, P., & Pedersen, O. (2004). Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes. Annals of Medicine, 36(5), pp. 355-66.
Gaede P, Pedersen O. Target Intervention Against Multiple-risk Markers to Reduce Cardiovascular Disease in Patients With Type 2 Diabetes. Ann Med. 2004;36(5):355-66. PubMed PMID: 15478310.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes. AU - Gaede,Peter, AU - Pedersen,Oluf, PY - 2004/10/14/pubmed PY - 2005/3/22/medline PY - 2004/10/14/entrez SP - 355 EP - 66 JF - Annals of medicine JO - Ann. Med. VL - 36 IS - 5 N2 - The risk of cardiovascular disease is markedly increased in patients with type 2 diabetes with a prevalence twice as high compared to the background population. With the recognition of multiple concomitant risk factors for both microvascular as well as cardiovascular disease in type 2 diabetic patients, treatment strategies have changed during recent years. This review focuses on the many recent drug trials that have set the course for an effective multifactorial treatment of the disease. Thus, the Steno-2 Study has shown that an intensified multifactorial intervention targeting several risk factors for cardiovascular disease is capable of reducing the risk for a combined endpoint of cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, coronary interventions, revascularisation to legs, and amputations by 50%. SN - 0785-3890 UR - https://www.unboundmedicine.com/medline/citation/15478310/Target_intervention_against_multiple_risk_markers_to_reduce_cardiovascular_disease_in_patients_with_type_2_diabetes_ L2 - http://www.tandfonline.com/doi/full/10.1080/07853890410033612 DB - PRIME DP - Unbound Medicine ER -