Tags

Type your tag names separated by a space and hit enter

Fat distribution, body mass index and blood pressure in 22,090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study.
J Hypertens 2004; 22(11):2067-74JH

Abstract

OBJECTIVE

To determine the relation between fat distribution and blood pressure, independent of body mass index.

DESIGN

Cross-sectional, population-based study.

PARTICIPANTS AND METHODS

Participants, 9936 men and 12,154 women aged 45-79 years, were recruited from general practices in Norfolk, United Kingdom for the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. Participants filled in a health and lifestyle questionnaire and their blood pressure and anthropometry were measured at a clinic. We mainly used waist-hip ratio (WHR) to assess body fat distribution.

RESULTS

Systolic blood pressure (SBP) and diastolic blood pressure (DBP) increased linearly across the whole range of waist-hip ratio in both men and women. The relation was independent of age, body mass index (BMI) and other covariates. Separately, waist and hip circumferences were positively related to SBP and DBP. When adjusted for BMI, waist circumference was positively related to SBP (in women) and DBP (in both men and women), whereas hip circumference was inversely related to SBP (but not DBP) in both men and women. Stratifying by tertiles of waist and hip circumference, age- and BMI-adjusted SBP and DBP were highest among those with high waist and small hip circumference measures.

CONCLUSION

Waist-hip ratio was independently related to blood pressure. Waist-hip ratio could reflect the separate and opposite relations of waist and hip circumferences on blood pressure. Characterizing patterns of fat distribution may have implications in the assessment and control of obesity-related blood pressure elevation.

Authors+Show Affiliations

Department of Public Health and Primary Care, University of Cambridge, Cambridge, MRC Dunn Human Nutrition Unit, Cambridge and MRC Epidemiology Unit, Cambridge, UK. dexter.canoy@srl.cam.ac.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15480089

Citation

Canoy, Dexter, et al. "Fat Distribution, Body Mass Index and Blood Pressure in 22,090 Men and Women in the Norfolk Cohort of the European Prospective Investigation Into Cancer and Nutrition (EPIC-Norfolk) Study." Journal of Hypertension, vol. 22, no. 11, 2004, pp. 2067-74.
Canoy D, Luben R, Welch A, et al. Fat distribution, body mass index and blood pressure in 22,090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. J Hypertens. 2004;22(11):2067-74.
Canoy, D., Luben, R., Welch, A., Bingham, S., Wareham, N., Day, N., & Khaw, K. T. (2004). Fat distribution, body mass index and blood pressure in 22,090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. Journal of Hypertension, 22(11), pp. 2067-74.
Canoy D, et al. Fat Distribution, Body Mass Index and Blood Pressure in 22,090 Men and Women in the Norfolk Cohort of the European Prospective Investigation Into Cancer and Nutrition (EPIC-Norfolk) Study. J Hypertens. 2004;22(11):2067-74. PubMed PMID: 15480089.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fat distribution, body mass index and blood pressure in 22,090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. AU - Canoy,Dexter, AU - Luben,Robert, AU - Welch,Ailsa, AU - Bingham,Sheila, AU - Wareham,Nicholas, AU - Day,Nicholas, AU - Khaw,Kay-Tee, PY - 2004/10/14/pubmed PY - 2005/2/17/medline PY - 2004/10/14/entrez SP - 2067 EP - 74 JF - Journal of hypertension JO - J. Hypertens. VL - 22 IS - 11 N2 - OBJECTIVE: To determine the relation between fat distribution and blood pressure, independent of body mass index. DESIGN: Cross-sectional, population-based study. PARTICIPANTS AND METHODS: Participants, 9936 men and 12,154 women aged 45-79 years, were recruited from general practices in Norfolk, United Kingdom for the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. Participants filled in a health and lifestyle questionnaire and their blood pressure and anthropometry were measured at a clinic. We mainly used waist-hip ratio (WHR) to assess body fat distribution. RESULTS: Systolic blood pressure (SBP) and diastolic blood pressure (DBP) increased linearly across the whole range of waist-hip ratio in both men and women. The relation was independent of age, body mass index (BMI) and other covariates. Separately, waist and hip circumferences were positively related to SBP and DBP. When adjusted for BMI, waist circumference was positively related to SBP (in women) and DBP (in both men and women), whereas hip circumference was inversely related to SBP (but not DBP) in both men and women. Stratifying by tertiles of waist and hip circumference, age- and BMI-adjusted SBP and DBP were highest among those with high waist and small hip circumference measures. CONCLUSION: Waist-hip ratio was independently related to blood pressure. Waist-hip ratio could reflect the separate and opposite relations of waist and hip circumferences on blood pressure. Characterizing patterns of fat distribution may have implications in the assessment and control of obesity-related blood pressure elevation. SN - 0263-6352 UR - https://www.unboundmedicine.com/medline/citation/15480089/Fat_distribution_body_mass_index_and_blood_pressure_in_22090_men_and_women_in_the_Norfolk_cohort_of_the_European_Prospective_Investigation_into_Cancer_and_Nutrition__EPIC_Norfolk__study_ L2 - http://Insights.ovid.com/pubmed?pmid=15480089 DB - PRIME DP - Unbound Medicine ER -