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Serum calcium and serum magnesium in normal and preeclamptic pregnancy.
Arch Gynecol Obstet. 2005 Nov; 273(1):12-6.AG

Abstract

OBJECTIVE

The aims of this study were to measure serum levels of calcium and magnesium in preeclamptic pregnancies and to compare them with those in normal pregnancies.

MATERIALS AND METHODS

We collected venous serum samples from 40 preeclamptic pregnant women and 40 normal pregnant women. The blood samples were analyzed for calcium and magnesium, using a colorimetric analyzer. The data were analyzed using the Student's t-test, chi2-test or Fisher exact tests when appropriate.

RESULTS

The serum calcium concentration in preeclamptic pregnant women is significantly lower than that in normal pregnant women (9.0 +/- 0.4 mg/dl vs. 9.7 +/- 0.7 mg/dl, p < 0.0001). Like serum calcium, serum magnesium concentration in preeclamptic women is significantly lower than that in normal pregnant women (0.77 +/- 0.08 mmol/l vs. 0.85 +/- 0.09 mmol/l, p = 0.001).

CONCLUSION

This study shows that both serum calcium and serum magnesium levels in preeclamptic pregnant women are lower than in normal pregnant women. These findings support the hypothesis that hypocalcemia and hypomagnesemia are possible etiologies of preeclampsia.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, Pathumwan, Bangkok, 10330, Thailand.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15480721

Citation

Sukonpan, Kanchapan, and Vorapong Phupong. "Serum Calcium and Serum Magnesium in Normal and Preeclamptic Pregnancy." Archives of Gynecology and Obstetrics, vol. 273, no. 1, 2005, pp. 12-6.
Sukonpan K, Phupong V. Serum calcium and serum magnesium in normal and preeclamptic pregnancy. Arch Gynecol Obstet. 2005;273(1):12-6.
Sukonpan, K., & Phupong, V. (2005). Serum calcium and serum magnesium in normal and preeclamptic pregnancy. Archives of Gynecology and Obstetrics, 273(1), 12-6.
Sukonpan K, Phupong V. Serum Calcium and Serum Magnesium in Normal and Preeclamptic Pregnancy. Arch Gynecol Obstet. 2005;273(1):12-6. PubMed PMID: 15480721.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum calcium and serum magnesium in normal and preeclamptic pregnancy. AU - Sukonpan,Kanchapan, AU - Phupong,Vorapong, Y1 - 2005/10/28/ PY - 2004/05/21/received PY - 2004/07/06/accepted PY - 2004/10/14/pubmed PY - 2007/1/26/medline PY - 2004/10/14/entrez SP - 12 EP - 6 JF - Archives of gynecology and obstetrics JO - Arch Gynecol Obstet VL - 273 IS - 1 N2 - OBJECTIVE: The aims of this study were to measure serum levels of calcium and magnesium in preeclamptic pregnancies and to compare them with those in normal pregnancies. MATERIALS AND METHODS: We collected venous serum samples from 40 preeclamptic pregnant women and 40 normal pregnant women. The blood samples were analyzed for calcium and magnesium, using a colorimetric analyzer. The data were analyzed using the Student's t-test, chi2-test or Fisher exact tests when appropriate. RESULTS: The serum calcium concentration in preeclamptic pregnant women is significantly lower than that in normal pregnant women (9.0 +/- 0.4 mg/dl vs. 9.7 +/- 0.7 mg/dl, p < 0.0001). Like serum calcium, serum magnesium concentration in preeclamptic women is significantly lower than that in normal pregnant women (0.77 +/- 0.08 mmol/l vs. 0.85 +/- 0.09 mmol/l, p = 0.001). CONCLUSION: This study shows that both serum calcium and serum magnesium levels in preeclamptic pregnant women are lower than in normal pregnant women. These findings support the hypothesis that hypocalcemia and hypomagnesemia are possible etiologies of preeclampsia. SN - 0932-0067 UR - https://www.unboundmedicine.com/medline/citation/15480721/Serum_calcium_and_serum_magnesium_in_normal_and_preeclamptic_pregnancy_ L2 - https://dx.doi.org/10.1007/s00404-004-0672-4 DB - PRIME DP - Unbound Medicine ER -