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Mediterranean diet and cognitive decline.
Public Health Nutr 2004; 7(7):959-63PH

Abstract

OBJECTIVE

To investigate the possible role of diet in age-related cognitive decline (ARCD) and cognitive impairment of both degenerative (Alzheimer's disease, AD) and vascular (vascular dementia, VaD) origin.

DESIGN

Literature review.

RESULTS

In an elderly population of southern Italy with a typical Mediterranean diet, high energy intake of monounsaturated fatty acids (MUFA) appeared to be associated with a high level of protection against ARCD. In addition, dietary fat and energy in the elderly seem to be risk factors, while fish consumption and cereals are found to reduce the prevalence of AD in European and North American countries. Finally, the relative risk of dementia (AD and VaD) was lower in the subjects of a French cohort who drank three or four glasses of red wine each day compared with total abstainers.

CONCLUSION

Essential components of the Mediterranean diet--MUFA, cereals and wine--seem to be protective against cognitive decline. As such, dietary antioxidants and supplements, specific macronutrients of the Mediterranean diet, oestrogens and anti-inflammatory drugs may act synergistically with other protective factors, opening up new therapeutic interventions for cognitive decline.

Authors+Show Affiliations

Department of Geriatrics, Center for Aging Brain, Memory Unit, University of Bari, Policlinico, Piazza Giulio Cesare 11, I-70124 Bari, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

15482625

Citation

Panza, F, et al. "Mediterranean Diet and Cognitive Decline." Public Health Nutrition, vol. 7, no. 7, 2004, pp. 959-63.
Panza F, Solfrizzi V, Colacicco AM, et al. Mediterranean diet and cognitive decline. Public Health Nutr. 2004;7(7):959-63.
Panza, F., Solfrizzi, V., Colacicco, A. M., D'Introno, A., Capurso, C., Torres, F., ... Capurso, A. (2004). Mediterranean diet and cognitive decline. Public Health Nutrition, 7(7), pp. 959-63.
Panza F, et al. Mediterranean Diet and Cognitive Decline. Public Health Nutr. 2004;7(7):959-63. PubMed PMID: 15482625.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mediterranean diet and cognitive decline. AU - Panza,F, AU - Solfrizzi,V, AU - Colacicco,A M, AU - D'Introno,A, AU - Capurso,C, AU - Torres,F, AU - Del Parigi,A, AU - Capurso,S, AU - Capurso,A, PY - 2004/10/16/pubmed PY - 2005/1/28/medline PY - 2004/10/16/entrez SP - 959 EP - 63 JF - Public health nutrition JO - Public Health Nutr VL - 7 IS - 7 N2 - OBJECTIVE: To investigate the possible role of diet in age-related cognitive decline (ARCD) and cognitive impairment of both degenerative (Alzheimer's disease, AD) and vascular (vascular dementia, VaD) origin. DESIGN: Literature review. RESULTS: In an elderly population of southern Italy with a typical Mediterranean diet, high energy intake of monounsaturated fatty acids (MUFA) appeared to be associated with a high level of protection against ARCD. In addition, dietary fat and energy in the elderly seem to be risk factors, while fish consumption and cereals are found to reduce the prevalence of AD in European and North American countries. Finally, the relative risk of dementia (AD and VaD) was lower in the subjects of a French cohort who drank three or four glasses of red wine each day compared with total abstainers. CONCLUSION: Essential components of the Mediterranean diet--MUFA, cereals and wine--seem to be protective against cognitive decline. As such, dietary antioxidants and supplements, specific macronutrients of the Mediterranean diet, oestrogens and anti-inflammatory drugs may act synergistically with other protective factors, opening up new therapeutic interventions for cognitive decline. SN - 1368-9800 UR - https://www.unboundmedicine.com/medline/citation/15482625/Mediterranean_diet_and_cognitive_decline_ L2 - https://www.cambridge.org/core/product/identifier/S1368980004001223/type/journal_article DB - PRIME DP - Unbound Medicine ER -