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Lassa virus.
Crit Rev Clin Lab Sci. 2004; 41(4):339-90.CR

Abstract

Lassa virus is a RNA virus belonging to the family of Arenaviridae. It was discovered as the causative agent of a hemorrhagic fever--Lassa fever--about 30 years ago. Lassa fever is endemic in West Africa and is estimated to affect some 100,000 people annually. Great progress in the understanding of the life cycle of arenaviruses, including Lassa virus, has been made in recent years. New insights have been gained in the pathogenesis and molecular epidemiology of Lassa fever, and state-of the-art technologies for diagnosing this life-threatening disease have been developed. The intention of this review is to summarize in particular the recent literature on Lassa virus and Lassa fever. Several aspects ranging from basic research up to clinical practice and laboratory diagnosis are discussed and linked together.

Authors+Show Affiliations

Department of Virology, Bernhard-Nocht-Institute of Tropical Medicine, Hamburg, Germany. guenther@bni.uni-hamburg.deNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

15487592

Citation

Günther, Stephan, and Oliver Lenz. "Lassa Virus." Critical Reviews in Clinical Laboratory Sciences, vol. 41, no. 4, 2004, pp. 339-90.
Günther S, Lenz O. Lassa virus. Crit Rev Clin Lab Sci. 2004;41(4):339-90.
Günther, S., & Lenz, O. (2004). Lassa virus. Critical Reviews in Clinical Laboratory Sciences, 41(4), 339-90.
Günther S, Lenz O. Lassa Virus. Crit Rev Clin Lab Sci. 2004;41(4):339-90. PubMed PMID: 15487592.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lassa virus. AU - Günther,Stephan, AU - Lenz,Oliver, PY - 2004/10/19/pubmed PY - 2005/3/2/medline PY - 2004/10/19/entrez SP - 339 EP - 90 JF - Critical reviews in clinical laboratory sciences JO - Crit Rev Clin Lab Sci VL - 41 IS - 4 N2 - Lassa virus is a RNA virus belonging to the family of Arenaviridae. It was discovered as the causative agent of a hemorrhagic fever--Lassa fever--about 30 years ago. Lassa fever is endemic in West Africa and is estimated to affect some 100,000 people annually. Great progress in the understanding of the life cycle of arenaviruses, including Lassa virus, has been made in recent years. New insights have been gained in the pathogenesis and molecular epidemiology of Lassa fever, and state-of the-art technologies for diagnosing this life-threatening disease have been developed. The intention of this review is to summarize in particular the recent literature on Lassa virus and Lassa fever. Several aspects ranging from basic research up to clinical practice and laboratory diagnosis are discussed and linked together. SN - 1040-8363 UR - https://www.unboundmedicine.com/medline/citation/15487592/full_citation L2 - http://www.tandfonline.com/doi/full/10.1080/10408360490497456 DB - PRIME DP - Unbound Medicine ER -