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Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control.
Int J Parasitol. 2004 Oct; 34(11):1205-10.IJ

Abstract

Control of soil-transmitted helminth infection and elimination of lymphatic filariasis by periodic chemotherapy increase drug pressure for possible occurrence of resistance against single dose anthelminthics. In veterinary practice, frequent treatment of closed populations has led to a serious problem of anthelminthic drug resistance which is now largely irreversible. Reduced efficacy of single dose drugs against nematodes of humans should be taken as early warnings to tackle the issue in due time. Research and development of sensitive tools for monitoring and early detection of drug resistance is urgently needed to sustain the benefits of helminth control programs gained so far. A concerted action with international partners and the creation of a network of scientists to address this issue is the next pressing public health issue for helminth control.

Authors+Show Affiliations

Fondazione Ivo de Carneri, Via IV Marzo 14, 10122 Torino, Italy. albonico@tin.itNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15491582

Citation

Albonico, Marco, et al. "Monitoring Drug Efficacy and Early Detection of Drug Resistance in Human Soil-transmitted Nematodes: a Pressing Public Health Agenda for Helminth Control." International Journal for Parasitology, vol. 34, no. 11, 2004, pp. 1205-10.
Albonico M, Engels D, Savioli L. Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control. Int J Parasitol. 2004;34(11):1205-10.
Albonico, M., Engels, D., & Savioli, L. (2004). Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control. International Journal for Parasitology, 34(11), 1205-10.
Albonico M, Engels D, Savioli L. Monitoring Drug Efficacy and Early Detection of Drug Resistance in Human Soil-transmitted Nematodes: a Pressing Public Health Agenda for Helminth Control. Int J Parasitol. 2004;34(11):1205-10. PubMed PMID: 15491582.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control. AU - Albonico,Marco, AU - Engels,Dirk, AU - Savioli,Lorenzo, PY - 2004/06/11/received PY - 2004/08/19/revised PY - 2004/08/19/accepted PY - 2004/10/20/pubmed PY - 2005/2/4/medline PY - 2004/10/20/entrez SP - 1205 EP - 10 JF - International journal for parasitology JO - Int J Parasitol VL - 34 IS - 11 N2 - Control of soil-transmitted helminth infection and elimination of lymphatic filariasis by periodic chemotherapy increase drug pressure for possible occurrence of resistance against single dose anthelminthics. In veterinary practice, frequent treatment of closed populations has led to a serious problem of anthelminthic drug resistance which is now largely irreversible. Reduced efficacy of single dose drugs against nematodes of humans should be taken as early warnings to tackle the issue in due time. Research and development of sensitive tools for monitoring and early detection of drug resistance is urgently needed to sustain the benefits of helminth control programs gained so far. A concerted action with international partners and the creation of a network of scientists to address this issue is the next pressing public health issue for helminth control. SN - 0020-7519 UR - https://www.unboundmedicine.com/medline/citation/15491582/Monitoring_drug_efficacy_and_early_detection_of_drug_resistance_in_human_soil_transmitted_nematodes:_a_pressing_public_health_agenda_for_helminth_control_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0020-7519(04)00165-1 DB - PRIME DP - Unbound Medicine ER -