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Association between lower urinary tract symptoms and erectile dysfunction.
Urology 2004; 64(4):772-6U

Abstract

OBJECTIVES

To assess whether the association between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) is confounded by age or whether LUTS represent an independent risk factor for ED.

METHODS

Men aged 20 to 80 years, who were participating in a health-screening project in the area of Vienna, completed the International Prostate Symptom Score (IPSS) and the International Index of Erectile Function-5. In parallel, all men underwent a detailed health evaluation, including physical examination, evaluation of various lifestyle factors, and a blood laboratory study with 14 parameters.

RESULTS

Within the total study population (n = 2858; mean age 45.8 years, range 20 to 80), the prevalence of LUTS and ED increased statistically significantly with age (P <0.0001). In multivariate analysis controlling for age, comorbidities, and lifestyle, the IPSS (P = 0.0001), the obstructive score of the IPSS (P = 0.0001), nocturia (P = 0.04), and the LUTS bother score (P = 0.002) correlated statistically significantly with the presence of ED (International Index of Erectile Function-5 score less than 22). The odds ratio for the presence of ED was 2.2 (95% confidence interval [CI] 1.8 to 2.8) for LUTS (IPSS greater than 7), 2.0 (95% CI 1.7 to 2.4) for voiding symptoms, 1.4 (95% CI 1.1 to 1.7) for nocturia (score greater than 2), and 2.5 (95% CI 2.0 to 3.1) for the LUTS bother score.

CONCLUSIONS

The presence of LUTS, in particular voiding symptoms, nocturia, and the quality-of-life impairment due to LUTS, is an independent risk factor for the presence of ED. These findings have implications for the treatment of elderly men with LUTS and open a new area for research.

Authors+Show Affiliations

Department of Preventive Health, City of Vienna, Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15491718

Citation

Ponholzer, Anton, et al. "Association Between Lower Urinary Tract Symptoms and Erectile Dysfunction." Urology, vol. 64, no. 4, 2004, pp. 772-6.
Ponholzer A, Temml C, Obermayr R, et al. Association between lower urinary tract symptoms and erectile dysfunction. Urology. 2004;64(4):772-6.
Ponholzer, A., Temml, C., Obermayr, R., & Madersbacher, S. (2004). Association between lower urinary tract symptoms and erectile dysfunction. Urology, 64(4), pp. 772-6.
Ponholzer A, et al. Association Between Lower Urinary Tract Symptoms and Erectile Dysfunction. Urology. 2004;64(4):772-6. PubMed PMID: 15491718.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association between lower urinary tract symptoms and erectile dysfunction. AU - Ponholzer,Anton, AU - Temml,Christian, AU - Obermayr,Rudolf, AU - Madersbacher,Stephan, PY - 2004/03/25/received PY - 2004/10/20/pubmed PY - 2005/8/13/medline PY - 2004/10/20/entrez SP - 772 EP - 6 JF - Urology JO - Urology VL - 64 IS - 4 N2 - OBJECTIVES: To assess whether the association between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) is confounded by age or whether LUTS represent an independent risk factor for ED. METHODS: Men aged 20 to 80 years, who were participating in a health-screening project in the area of Vienna, completed the International Prostate Symptom Score (IPSS) and the International Index of Erectile Function-5. In parallel, all men underwent a detailed health evaluation, including physical examination, evaluation of various lifestyle factors, and a blood laboratory study with 14 parameters. RESULTS: Within the total study population (n = 2858; mean age 45.8 years, range 20 to 80), the prevalence of LUTS and ED increased statistically significantly with age (P <0.0001). In multivariate analysis controlling for age, comorbidities, and lifestyle, the IPSS (P = 0.0001), the obstructive score of the IPSS (P = 0.0001), nocturia (P = 0.04), and the LUTS bother score (P = 0.002) correlated statistically significantly with the presence of ED (International Index of Erectile Function-5 score less than 22). The odds ratio for the presence of ED was 2.2 (95% confidence interval [CI] 1.8 to 2.8) for LUTS (IPSS greater than 7), 2.0 (95% CI 1.7 to 2.4) for voiding symptoms, 1.4 (95% CI 1.1 to 1.7) for nocturia (score greater than 2), and 2.5 (95% CI 2.0 to 3.1) for the LUTS bother score. CONCLUSIONS: The presence of LUTS, in particular voiding symptoms, nocturia, and the quality-of-life impairment due to LUTS, is an independent risk factor for the presence of ED. These findings have implications for the treatment of elderly men with LUTS and open a new area for research. SN - 1527-9995 UR - https://www.unboundmedicine.com/medline/citation/15491718/Association_between_lower_urinary_tract_symptoms_and_erectile_dysfunction_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0090-4295(04)00677-6 DB - PRIME DP - Unbound Medicine ER -