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Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea.

Abstract

OBJECTIVE

To determine if pain relief provided by a wearable heat wrap (continuous, low-level, topical heat therapy) is superior to oral acetaminophen for primary dysmenorrhea.

STUDY DESIGN

A randomized, active-controlled, multisite, single-blind (investigator), parallel-design study compared an abdominal wrap to an oral medication (acetaminophen, 1000 mg) over I day. Pain relief (0-5) and abdominal muscle tightness/cramping (0-100) were recorded at 12 time points. At 24 and 48 hours, menstrual symptom-based quality of life was assessed.

RESULTS

Three hundred sixty-seven subjects entered the study, with 344 subjects evaluable. The heat wrap was superior to acetaminophen for pain relief over an 8-hour period (means of 2.48 and 2.17, p = 0.015) and at t hours 3, 4, 5 and 6 (p < or = 0.05). Tightness/cramping was less for the heat wrap versus acetaminophen over 8 hours (means of 40.4 and 44.5, p = 0.04) and at hours 4, 5 and 6 (p < or = 0.05). There was significantly decreased fatigue, fewer mood swings and less lower abdominal cramping (p < or = 0.05) with heat therapy.

CONCLUSION

Continuous, low-level, topical heat therapy was superior to acetaminophen for the treatment of dysmenorrhea.

Authors+Show Affiliations

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CEDRA Clinical Research, LLC, Austin, Texas, USA.

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Source

The Journal of reproductive medicine 49:9 2004 Sep pg 739-45

MeSH

Acetaminophen
Adult
Analgesics, Non-Narcotic
Dysmenorrhea
Female
Hot Temperature
Humans
Multivariate Analysis
Pain Measurement
Severity of Illness Index
Single-Blind Method
Time Factors
Treatment Outcome

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15493566

Citation

Akin, Mark, et al. "Continuous, Low-level, Topical Heat Wrap Therapy as Compared to Acetaminophen for Primary Dysmenorrhea." The Journal of Reproductive Medicine, vol. 49, no. 9, 2004, pp. 739-45.
Akin M, Price W, Rodriguez G, et al. Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea. J Reprod Med. 2004;49(9):739-45.
Akin, M., Price, W., Rodriguez, G., Erasala, G., Hurley, G., & Smith, R. P. (2004). Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea. The Journal of Reproductive Medicine, 49(9), pp. 739-45.
Akin M, et al. Continuous, Low-level, Topical Heat Wrap Therapy as Compared to Acetaminophen for Primary Dysmenorrhea. J Reprod Med. 2004;49(9):739-45. PubMed PMID: 15493566.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea. AU - Akin,Mark, AU - Price,William, AU - Rodriguez,Gonzalo,Jr AU - Erasala,Geetha, AU - Hurley,George, AU - Smith,Roger P, PY - 2004/10/21/pubmed PY - 2004/12/22/medline PY - 2004/10/21/entrez SP - 739 EP - 45 JF - The Journal of reproductive medicine JO - J Reprod Med VL - 49 IS - 9 N2 - OBJECTIVE: To determine if pain relief provided by a wearable heat wrap (continuous, low-level, topical heat therapy) is superior to oral acetaminophen for primary dysmenorrhea. STUDY DESIGN: A randomized, active-controlled, multisite, single-blind (investigator), parallel-design study compared an abdominal wrap to an oral medication (acetaminophen, 1000 mg) over I day. Pain relief (0-5) and abdominal muscle tightness/cramping (0-100) were recorded at 12 time points. At 24 and 48 hours, menstrual symptom-based quality of life was assessed. RESULTS: Three hundred sixty-seven subjects entered the study, with 344 subjects evaluable. The heat wrap was superior to acetaminophen for pain relief over an 8-hour period (means of 2.48 and 2.17, p = 0.015) and at t hours 3, 4, 5 and 6 (p < or = 0.05). Tightness/cramping was less for the heat wrap versus acetaminophen over 8 hours (means of 40.4 and 44.5, p = 0.04) and at hours 4, 5 and 6 (p < or = 0.05). There was significantly decreased fatigue, fewer mood swings and less lower abdominal cramping (p < or = 0.05) with heat therapy. CONCLUSION: Continuous, low-level, topical heat therapy was superior to acetaminophen for the treatment of dysmenorrhea. SN - 0024-7758 UR - https://www.unboundmedicine.com/medline/citation/15493566/full_citation L2 - https://ClinicalTrials.gov/search/term=15493566 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -