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Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea.
J Reprod Med 2004; 49(9):739-45JR

Abstract

OBJECTIVE

To determine if pain relief provided by a wearable heat wrap (continuous, low-level, topical heat therapy) is superior to oral acetaminophen for primary dysmenorrhea.

STUDY DESIGN

A randomized, active-controlled, multisite, single-blind (investigator), parallel-design study compared an abdominal wrap to an oral medication (acetaminophen, 1000 mg) over I day. Pain relief (0-5) and abdominal muscle tightness/cramping (0-100) were recorded at 12 time points. At 24 and 48 hours, menstrual symptom-based quality of life was assessed.

RESULTS

Three hundred sixty-seven subjects entered the study, with 344 subjects evaluable. The heat wrap was superior to acetaminophen for pain relief over an 8-hour period (means of 2.48 and 2.17, p = 0.015) and at t hours 3, 4, 5 and 6 (p < or = 0.05). Tightness/cramping was less for the heat wrap versus acetaminophen over 8 hours (means of 40.4 and 44.5, p = 0.04) and at hours 4, 5 and 6 (p < or = 0.05). There was significantly decreased fatigue, fewer mood swings and less lower abdominal cramping (p < or = 0.05) with heat therapy.

CONCLUSION

Continuous, low-level, topical heat therapy was superior to acetaminophen for the treatment of dysmenorrhea.

Authors+Show Affiliations

CEDRA Clinical Research, LLC, Austin, Texas, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15493566

Citation

Akin, Mark, et al. "Continuous, Low-level, Topical Heat Wrap Therapy as Compared to Acetaminophen for Primary Dysmenorrhea." The Journal of Reproductive Medicine, vol. 49, no. 9, 2004, pp. 739-45.
Akin M, Price W, Rodriguez G, et al. Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea. J Reprod Med. 2004;49(9):739-45.
Akin, M., Price, W., Rodriguez, G., Erasala, G., Hurley, G., & Smith, R. P. (2004). Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea. The Journal of Reproductive Medicine, 49(9), pp. 739-45.
Akin M, et al. Continuous, Low-level, Topical Heat Wrap Therapy as Compared to Acetaminophen for Primary Dysmenorrhea. J Reprod Med. 2004;49(9):739-45. PubMed PMID: 15493566.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea. AU - Akin,Mark, AU - Price,William, AU - Rodriguez,Gonzalo,Jr AU - Erasala,Geetha, AU - Hurley,George, AU - Smith,Roger P, PY - 2004/10/21/pubmed PY - 2004/12/22/medline PY - 2004/10/21/entrez SP - 739 EP - 45 JF - The Journal of reproductive medicine JO - J Reprod Med VL - 49 IS - 9 N2 - OBJECTIVE: To determine if pain relief provided by a wearable heat wrap (continuous, low-level, topical heat therapy) is superior to oral acetaminophen for primary dysmenorrhea. STUDY DESIGN: A randomized, active-controlled, multisite, single-blind (investigator), parallel-design study compared an abdominal wrap to an oral medication (acetaminophen, 1000 mg) over I day. Pain relief (0-5) and abdominal muscle tightness/cramping (0-100) were recorded at 12 time points. At 24 and 48 hours, menstrual symptom-based quality of life was assessed. RESULTS: Three hundred sixty-seven subjects entered the study, with 344 subjects evaluable. The heat wrap was superior to acetaminophen for pain relief over an 8-hour period (means of 2.48 and 2.17, p = 0.015) and at t hours 3, 4, 5 and 6 (p < or = 0.05). Tightness/cramping was less for the heat wrap versus acetaminophen over 8 hours (means of 40.4 and 44.5, p = 0.04) and at hours 4, 5 and 6 (p < or = 0.05). There was significantly decreased fatigue, fewer mood swings and less lower abdominal cramping (p < or = 0.05) with heat therapy. CONCLUSION: Continuous, low-level, topical heat therapy was superior to acetaminophen for the treatment of dysmenorrhea. SN - 0024-7758 UR - https://www.unboundmedicine.com/medline/citation/15493566/full_citation L2 - https://ClinicalTrials.gov/search/term=15493566 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -