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Extraction of valerenic acids from valerian (Valeriana officinalis L.) rhizomes.
Pharmazie. 2004 Sep; 59(9):727-8.P

Abstract

Extraction of valerenic acids (valerenic, acetoxyvalerenic and hydroxyvalerenic) from dry ground rhizomes of valerian (Valeriana officinalis L.) was studied. The effect of ethanol concentration in the solvent, extraction temperature and drug particle size on extraction kinetics were investigated and the optimum values of these process parameters were determined for the case of intensively stirred two-phase dispersion. It was found that increased processing temperature favors extraction kinetics, but provokes moderate degradation of valerenic acids.

Authors+Show Affiliations

Institute of Chemical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria. lboyadz@bas.bgNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15497760

Citation

Boyadzhiev, L, et al. "Extraction of Valerenic Acids From Valerian (Valeriana Officinalis L.) Rhizomes." Die Pharmazie, vol. 59, no. 9, 2004, pp. 727-8.
Boyadzhiev L, Kancheva D, Gourdon C, et al. Extraction of valerenic acids from valerian (Valeriana officinalis L.) rhizomes. Pharmazie. 2004;59(9):727-8.
Boyadzhiev, L., Kancheva, D., Gourdon, C., & Metcheva, D. (2004). Extraction of valerenic acids from valerian (Valeriana officinalis L.) rhizomes. Die Pharmazie, 59(9), 727-8.
Boyadzhiev L, et al. Extraction of Valerenic Acids From Valerian (Valeriana Officinalis L.) Rhizomes. Pharmazie. 2004;59(9):727-8. PubMed PMID: 15497760.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extraction of valerenic acids from valerian (Valeriana officinalis L.) rhizomes. AU - Boyadzhiev,L, AU - Kancheva,D, AU - Gourdon,C, AU - Metcheva,D, PY - 2004/10/23/pubmed PY - 2004/12/16/medline PY - 2004/10/23/entrez SP - 727 EP - 8 JF - Die Pharmazie JO - Pharmazie VL - 59 IS - 9 N2 - Extraction of valerenic acids (valerenic, acetoxyvalerenic and hydroxyvalerenic) from dry ground rhizomes of valerian (Valeriana officinalis L.) was studied. The effect of ethanol concentration in the solvent, extraction temperature and drug particle size on extraction kinetics were investigated and the optimum values of these process parameters were determined for the case of intensively stirred two-phase dispersion. It was found that increased processing temperature favors extraction kinetics, but provokes moderate degradation of valerenic acids. SN - 0031-7144 UR - https://www.unboundmedicine.com/medline/citation/15497760/Extraction_of_valerenic_acids_from_valerian__Valeriana_officinalis_L___rhizomes_ L2 - https://www.lens.org/lens/search/patent/list?q=citation_id:15497760 DB - PRIME DP - Unbound Medicine ER -