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A prospective study of Type 2 diabetes and depressive symptoms in the elderly: the Rancho Bernardo Study.
Diabet Med 2004; 21(11):1185-91DM

Abstract

AIMS

The association between Type 2 diabetes and depressive symptoms was examined prospectively to assess possible causal relationships between the two diseases.

METHODS

A cohort of 971 men and women aged 50 and older from the adult population of Rancho Bernardo, California had an oral glucose tolerance test and completed the Beck Depression Inventory (BDI) at two clinic visits, 1984-87 and 1992-96.

RESULTS

Depressive symptoms at baseline were associated with higher follow-up levels of non-fasting plasma glucose (P = 0.001) and an increased risk of developing Type 2 diabetes [odds ratio (OR) = 2.50; 95% confidence interval (CI) = 1.29-4.87], independent of sex, age, exercise and body mass index. Conversely, baseline non-fasting plasma glucose was not significantly associated with follow-up depressive symptoms and Type 2 diabetes at baseline was not significantly associated with the onset of BDI scores > or = 11 by the second visit (OR = 0.73; 95% CI = 0.41-1.30).

CONCLUSIONS

Depressed mood is more likely to be a risk factor for Type 2 diabetes in older adults than the reverse.

Authors+Show Affiliations

Department of Family and Preventive Medicine, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0622, USA. lpalinkas@ucsd.edu

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15498084

Citation

Palinkas, L A., et al. "A Prospective Study of Type 2 Diabetes and Depressive Symptoms in the Elderly: the Rancho Bernardo Study." Diabetic Medicine : a Journal of the British Diabetic Association, vol. 21, no. 11, 2004, pp. 1185-91.
Palinkas LA, Lee PP, Barrett-Connor E. A prospective study of Type 2 diabetes and depressive symptoms in the elderly: the Rancho Bernardo Study. Diabet Med. 2004;21(11):1185-91.
Palinkas, L. A., Lee, P. P., & Barrett-Connor, E. (2004). A prospective study of Type 2 diabetes and depressive symptoms in the elderly: the Rancho Bernardo Study. Diabetic Medicine : a Journal of the British Diabetic Association, 21(11), pp. 1185-91.
Palinkas LA, Lee PP, Barrett-Connor E. A Prospective Study of Type 2 Diabetes and Depressive Symptoms in the Elderly: the Rancho Bernardo Study. Diabet Med. 2004;21(11):1185-91. PubMed PMID: 15498084.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A prospective study of Type 2 diabetes and depressive symptoms in the elderly: the Rancho Bernardo Study. AU - Palinkas,L A, AU - Lee,P P, AU - Barrett-Connor,E, PY - 2004/10/23/pubmed PY - 2005/1/26/medline PY - 2004/10/23/entrez SP - 1185 EP - 91 JF - Diabetic medicine : a journal of the British Diabetic Association JO - Diabet. Med. VL - 21 IS - 11 N2 - AIMS: The association between Type 2 diabetes and depressive symptoms was examined prospectively to assess possible causal relationships between the two diseases. METHODS: A cohort of 971 men and women aged 50 and older from the adult population of Rancho Bernardo, California had an oral glucose tolerance test and completed the Beck Depression Inventory (BDI) at two clinic visits, 1984-87 and 1992-96. RESULTS: Depressive symptoms at baseline were associated with higher follow-up levels of non-fasting plasma glucose (P = 0.001) and an increased risk of developing Type 2 diabetes [odds ratio (OR) = 2.50; 95% confidence interval (CI) = 1.29-4.87], independent of sex, age, exercise and body mass index. Conversely, baseline non-fasting plasma glucose was not significantly associated with follow-up depressive symptoms and Type 2 diabetes at baseline was not significantly associated with the onset of BDI scores > or = 11 by the second visit (OR = 0.73; 95% CI = 0.41-1.30). CONCLUSIONS: Depressed mood is more likely to be a risk factor for Type 2 diabetes in older adults than the reverse. SN - 0742-3071 UR - https://www.unboundmedicine.com/medline/citation/15498084/A_prospective_study_of_Type_2_diabetes_and_depressive_symptoms_in_the_elderly:_the_Rancho_Bernardo_Study_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=15498084.ui DB - PRIME DP - Unbound Medicine ER -