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[Nephrotic syndrome: pathophysiology, classification and diagnostic criteria].
Nihon Rinsho. 2004 Oct; 62(10):1777-83.NR

Abstract

The nephrotic syndrome is defined by heavy proteinuria due to abnormal increase of glomerular permeability and following hypoalbuminemia, hyperlipidemia and edema. Disorders of size selective barrier, charge selective barrier, slit diaphragm and circulating permeability factors are thought to be the causes of proteinuria. Most patients with nephrotic edema have primary salt retention. Overproduction and impaired catabolism of lipoproteins are the causes of hyperlipidemia. Abnormality of coagulation factors is also associated with nephrotic syndrome. Nephrotic syndrome may be primary or secondary to systemic disorders. Once diagnosed, the cause for the nephrotic syndrome must be examined.

Authors+Show Affiliations

First Department of Medicine, Hamamatsu University School of Medicine.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

jpn

PubMed ID

15500118

Citation

Togawa, Akashi, et al. "[Nephrotic Syndrome: Pathophysiology, Classification and Diagnostic Criteria]." Nihon Rinsho. Japanese Journal of Clinical Medicine, vol. 62, no. 10, 2004, pp. 1777-83.
Togawa A, Yamamoto T, Hishida A. [Nephrotic syndrome: pathophysiology, classification and diagnostic criteria]. Nippon Rinsho. 2004;62(10):1777-83.
Togawa, A., Yamamoto, T., & Hishida, A. (2004). [Nephrotic syndrome: pathophysiology, classification and diagnostic criteria]. Nihon Rinsho. Japanese Journal of Clinical Medicine, 62(10), 1777-83.
Togawa A, Yamamoto T, Hishida A. [Nephrotic Syndrome: Pathophysiology, Classification and Diagnostic Criteria]. Nippon Rinsho. 2004;62(10):1777-83. PubMed PMID: 15500118.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Nephrotic syndrome: pathophysiology, classification and diagnostic criteria]. AU - Togawa,Akashi, AU - Yamamoto,Tatsuo, AU - Hishida,Akira, PY - 2004/10/27/pubmed PY - 2004/12/16/medline PY - 2004/10/27/entrez SP - 1777 EP - 83 JF - Nihon rinsho. Japanese journal of clinical medicine JO - Nippon Rinsho VL - 62 IS - 10 N2 - The nephrotic syndrome is defined by heavy proteinuria due to abnormal increase of glomerular permeability and following hypoalbuminemia, hyperlipidemia and edema. Disorders of size selective barrier, charge selective barrier, slit diaphragm and circulating permeability factors are thought to be the causes of proteinuria. Most patients with nephrotic edema have primary salt retention. Overproduction and impaired catabolism of lipoproteins are the causes of hyperlipidemia. Abnormality of coagulation factors is also associated with nephrotic syndrome. Nephrotic syndrome may be primary or secondary to systemic disorders. Once diagnosed, the cause for the nephrotic syndrome must be examined. SN - 0047-1852 UR - https://www.unboundmedicine.com/medline/citation/15500118/[Nephrotic_syndrome:_pathophysiology_classification_and_diagnostic_criteria]_ DB - PRIME DP - Unbound Medicine ER -