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Effects of long-term monounsaturated- vs polyunsaturated-enriched diets on lipoproteins in healthy men and women.
Am J Clin Nutr. 1992 Apr; 55(4):846-50.AJ

Abstract

The effect of dietary-fat saturation on plasma lipoprotein concentrations was assessed in 46 men and 32 women placed on a diet enriched in polyunsaturated fatty acids (sunflower oil) for 12 wk and, under isocaloric conditions, on a diet enriched in monounsaturated fatty acids (olive oil) for the next 16 wk in men and 28 wk in women. Fat comprised 37% of the total energy intake in men and 36% in women. At the end of the monounsaturated fatty acid diet no change occurred in total cholesterol (TC) in men but it increased by 9% in women. High-density-lipoprotein (HDL) cholesterol increased by 17% in men and by 30% in women. The atherogenic index (TC:HDL cholesterol) fell significantly in both sexes. No significant changes occurred in plasma low-density-lipoprotein cholesterol or in total triglycerides values. These data show that when compared with polyunsaturates, monounsaturates increased HDL cholesterol and reduced the atherogenic risk profile in both sexes.

Authors+Show Affiliations

Department of Internal Medicine, Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1550067

Citation

Mata, P, et al. "Effects of Long-term Monounsaturated- Vs Polyunsaturated-enriched Diets On Lipoproteins in Healthy Men and Women." The American Journal of Clinical Nutrition, vol. 55, no. 4, 1992, pp. 846-50.
Mata P, Alvarez-Sala LA, Rubio MJ, et al. Effects of long-term monounsaturated- vs polyunsaturated-enriched diets on lipoproteins in healthy men and women. Am J Clin Nutr. 1992;55(4):846-50.
Mata, P., Alvarez-Sala, L. A., Rubio, M. J., Nuño, J., & De Oya, M. (1992). Effects of long-term monounsaturated- vs polyunsaturated-enriched diets on lipoproteins in healthy men and women. The American Journal of Clinical Nutrition, 55(4), 846-50.
Mata P, et al. Effects of Long-term Monounsaturated- Vs Polyunsaturated-enriched Diets On Lipoproteins in Healthy Men and Women. Am J Clin Nutr. 1992;55(4):846-50. PubMed PMID: 1550067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of long-term monounsaturated- vs polyunsaturated-enriched diets on lipoproteins in healthy men and women. AU - Mata,P, AU - Alvarez-Sala,L A, AU - Rubio,M J, AU - Nuño,J, AU - De Oya,M, PY - 1992/4/1/pubmed PY - 1992/4/1/medline PY - 1992/4/1/entrez SP - 846 EP - 50 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 55 IS - 4 N2 - The effect of dietary-fat saturation on plasma lipoprotein concentrations was assessed in 46 men and 32 women placed on a diet enriched in polyunsaturated fatty acids (sunflower oil) for 12 wk and, under isocaloric conditions, on a diet enriched in monounsaturated fatty acids (olive oil) for the next 16 wk in men and 28 wk in women. Fat comprised 37% of the total energy intake in men and 36% in women. At the end of the monounsaturated fatty acid diet no change occurred in total cholesterol (TC) in men but it increased by 9% in women. High-density-lipoprotein (HDL) cholesterol increased by 17% in men and by 30% in women. The atherogenic index (TC:HDL cholesterol) fell significantly in both sexes. No significant changes occurred in plasma low-density-lipoprotein cholesterol or in total triglycerides values. These data show that when compared with polyunsaturates, monounsaturates increased HDL cholesterol and reduced the atherogenic risk profile in both sexes. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/1550067/Effects_of_long_term_monounsaturated__vs_polyunsaturated_enriched_diets_on_lipoproteins_in_healthy_men_and_women_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/55.4.846 DB - PRIME DP - Unbound Medicine ER -