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Kahiricosides II-V, cycloartane glycosides from an Egyptian collection of Astragalus kahiricus.
Phytochemistry. 2004 Nov; 65(21):2909-13.P

Abstract

Four cycloartane-type saponins, kahiricosides II-V (1-4), were isolated from the aerial parts of Astragalus kahiricus of Egyptian origin. Their structures were established as 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-beta-D-glucopyranoside, 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-(2'-O-acetyl)-beta-D-glucopyranoside, 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-(6'-O-acetyl)-beta-D-glucopyranoside, and 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-beta-D-glucopyranosyl-27-O-beta-D-glucopyranoside based on chemical and spectral evidences. All compounds exhibited very weak cytotoxicity against the A2780 ovarian cancer cell line.

Authors+Show Affiliations

Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, 3111 Hahn Hall, MC 0212, Blacksburg, VA 24061-0212, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15501260

Citation

Radwan, Mohamed M., et al. "Kahiricosides II-V, Cycloartane Glycosides From an Egyptian Collection of Astragalus Kahiricus." Phytochemistry, vol. 65, no. 21, 2004, pp. 2909-13.
Radwan MM, El-Sebakhy NA, Asaad AM, et al. Kahiricosides II-V, cycloartane glycosides from an Egyptian collection of Astragalus kahiricus. Phytochemistry. 2004;65(21):2909-13.
Radwan, M. M., El-Sebakhy, N. A., Asaad, A. M., Toaima, S. M., & Kingston, D. G. (2004). Kahiricosides II-V, cycloartane glycosides from an Egyptian collection of Astragalus kahiricus. Phytochemistry, 65(21), 2909-13.
Radwan MM, et al. Kahiricosides II-V, Cycloartane Glycosides From an Egyptian Collection of Astragalus Kahiricus. Phytochemistry. 2004;65(21):2909-13. PubMed PMID: 15501260.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Kahiricosides II-V, cycloartane glycosides from an Egyptian collection of Astragalus kahiricus. AU - Radwan,Mohamed M, AU - El-Sebakhy,Nadia A, AU - Asaad,Aya M, AU - Toaima,Soad M, AU - Kingston,David G I, PY - 2004/04/14/received PY - 2004/07/27/revised PY - 2004/10/27/pubmed PY - 2005/1/15/medline PY - 2004/10/27/entrez SP - 2909 EP - 13 JF - Phytochemistry JO - Phytochemistry VL - 65 IS - 21 N2 - Four cycloartane-type saponins, kahiricosides II-V (1-4), were isolated from the aerial parts of Astragalus kahiricus of Egyptian origin. Their structures were established as 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-beta-D-glucopyranoside, 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-(2'-O-acetyl)-beta-D-glucopyranoside, 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-(6'-O-acetyl)-beta-D-glucopyranoside, and 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-beta-D-glucopyranosyl-27-O-beta-D-glucopyranoside based on chemical and spectral evidences. All compounds exhibited very weak cytotoxicity against the A2780 ovarian cancer cell line. SN - 0031-9422 UR - https://www.unboundmedicine.com/medline/citation/15501260/Kahiricosides_II_V_cycloartane_glycosides_from_an_Egyptian_collection_of_Astragalus_kahiricus_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0031-9422(04)00418-2 DB - PRIME DP - Unbound Medicine ER -