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Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China.
Emerg Infect Dis. 2004 Oct; 10(10):1774-81.EI

Abstract

Four cases of severe acute respiratory syndrome (SARS) that occurred from December 16, 2003, to January 8, 2004, in the city of Guangzhou, Guangdong Province, China, were investigated. Clinical specimens collected from these patients were tested by provincial and national laboratories in China as well as members of the World Health Organization SARS Reference and Verification Laboratory Network in a collaborative effort to identify and confirm SARS-associated coronavirus (SARS-CoV) infection. Although SARS-CoV was not isolated from any patient, specimens from three patients were positive for viral RNA by reverse transcription-polymerase chain reaction assay, and all patients had detectable rises in SARS-CoV-specific antibodies. This study shows the effectiveness of a collaborative, multilaboratory response to diagnose SARS.

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Authors+Show Affiliations

Liang G
Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.
Chen Q
No affiliation info available
Xu J
No affiliation info available
Liu Y
No affiliation info available
Lim W
No affiliation info available
Peiris JS
No affiliation info available
Anderson LJ
No affiliation info available
Ruan L
No affiliation info available
Li H
No affiliation info available
Kan B
No affiliation info available
Di B
No affiliation info available
Cheng P
No affiliation info available
Chan KH
No affiliation info available
Erdman DD
No affiliation info available
Gu S
No affiliation info available
Yan X
No affiliation info available
Liang W
No affiliation info available
Zhou D
No affiliation info available
Haynes L
No affiliation info available
Duan S
No affiliation info available
Zhang X
No affiliation info available
Zheng H
No affiliation info available
Gao Y
No affiliation info available
Tong S
No affiliation info available
Li D
No affiliation info available
Fang L
No affiliation info available
Qin P
No affiliation info available
Xu W
No affiliation info available
SARS Diagnosis Working Group
No affiliation info available

MeSH

AdultAntibodies, ViralChinaFecesFemaleHumansMaleRNA, ViralSevere acute respiratory syndrome-related coronavirusSevere Acute Respiratory Syndrome

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15504263

Citation

Liang, Guodong, et al. "Laboratory Diagnosis of Four Recent Sporadic Cases of Community-acquired SARS, Guangdong Province, China." Emerging Infectious Diseases, vol. 10, no. 10, 2004, pp. 1774-81.
Liang G, Chen Q, Xu J, et al. Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerg Infect Dis. 2004;10(10):1774-81.
Liang, G., Chen, Q., Xu, J., Liu, Y., Lim, W., Peiris, J. S., Anderson, L. J., Ruan, L., Li, H., Kan, B., Di, B., Cheng, P., Chan, K. H., Erdman, D. D., Gu, S., Yan, X., Liang, W., Zhou, D., Haynes, L., ... Xu, W. (2004). Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerging Infectious Diseases, 10(10), 1774-81.
Liang G, et al. Laboratory Diagnosis of Four Recent Sporadic Cases of Community-acquired SARS, Guangdong Province, China. Emerg Infect Dis. 2004;10(10):1774-81. PubMed PMID: 15504263.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. AU - Liang,Guodong, AU - Chen,Qiuxia, AU - Xu,Jianguo, AU - Liu,Yufei, AU - Lim,Wilina, AU - Peiris,J S M, AU - Anderson,Larry J, AU - Ruan,Li, AU - Li,Hui, AU - Kan,Biao, AU - Di,Biao, AU - Cheng,Peter, AU - Chan,K H, AU - Erdman,Dean D, AU - Gu,Shuyan, AU - Yan,Xinge, AU - Liang,Weili, AU - Zhou,Duanhua, AU - Haynes,Lia, AU - Duan,Shumin, AU - Zhang,Xin, AU - Zheng,Han, AU - Gao,Yang, AU - Tong,Suxiang, AU - Li,Dexin, AU - Fang,Ling, AU - Qin,Pengzhe, AU - Xu,Wenbo, AU - ,, PY - 2004/10/27/pubmed PY - 2004/12/16/medline PY - 2004/10/27/entrez SP - 1774 EP - 81 JF - Emerging infectious diseases JO - Emerg Infect Dis VL - 10 IS - 10 N2 - Four cases of severe acute respiratory syndrome (SARS) that occurred from December 16, 2003, to January 8, 2004, in the city of Guangzhou, Guangdong Province, China, were investigated. Clinical specimens collected from these patients were tested by provincial and national laboratories in China as well as members of the World Health Organization SARS Reference and Verification Laboratory Network in a collaborative effort to identify and confirm SARS-associated coronavirus (SARS-CoV) infection. Although SARS-CoV was not isolated from any patient, specimens from three patients were positive for viral RNA by reverse transcription-polymerase chain reaction assay, and all patients had detectable rises in SARS-CoV-specific antibodies. This study shows the effectiveness of a collaborative, multilaboratory response to diagnose SARS. SN - 1080-6040 UR - https://www.unboundmedicine.com/medline/citation/15504263/Laboratory_diagnosis_of_four_recent_sporadic_cases_of_community_acquired_SARS_Guangdong_Province_China_ DB - PRIME DP - Unbound Medicine ER -