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[Non alcoholic steatohepatitis: an emergent and potentially serious pathology].
Tunis Med. 2004 Jun; 82(6):484-91.TM

Abstract

Nonalcoholic steatohepatitis is an acquired liver disease, usually metabolic characterised by histologic lesions with steatosis, intralobular necrosis and inflammatory infiltrates. Liver biopsy findings are identical to those seen in alcoholic hepatitis. Nonalcoholic steatohepatitis is increasingly reported in industrial countries because of an increase of the prevalence of obesity and diabetes which are the most common risk factors of this disease. The diagnosis of nonalcoholic steatohepatitis is based on a confrontation between clinical and anatomic data and an exclusion of an excessive intake of alcohol and other hepatic disease. Liver biopsy has a prognosis and histologic benefit especially when there is risk factors of fibrosis. This disease is potentially severe with a potential risk for progression to cirrhosis. Progress in pathogenesis is noted but no definite therapy exist. The aim of this review is to indicate current knowledge for the gravity of nonalcoholic steatohepatitis and its consequence and to understand the pathogenesis to prevent cirrhosis.

Authors+Show Affiliations

Hôpital universitaire Sahlout, Sousse Tunisie: Service de Gastro-entérologie.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

15517946

Citation

Elloumi, Héla, et al. "[Non Alcoholic Steatohepatitis: an Emergent and Potentially Serious Pathology]." La Tunisie Medicale, vol. 82, no. 6, 2004, pp. 484-91.
Elloumi H, Arfaoui D, Joudène M, et al. [Non alcoholic steatohepatitis: an emergent and potentially serious pathology]. Tunis Med. 2004;82(6):484-91.
Elloumi, H., Arfaoui, D., Joudène, M., Sriha, B., Korbi, M., & Ajmi, S. (2004). [Non alcoholic steatohepatitis: an emergent and potentially serious pathology]. La Tunisie Medicale, 82(6), 484-91.
Elloumi H, et al. [Non Alcoholic Steatohepatitis: an Emergent and Potentially Serious Pathology]. Tunis Med. 2004;82(6):484-91. PubMed PMID: 15517946.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Non alcoholic steatohepatitis: an emergent and potentially serious pathology]. AU - Elloumi,Héla, AU - Arfaoui,Dalenda, AU - Joudène,Mehdi, AU - Sriha,Badreddine, AU - Korbi,Muncef, AU - Ajmi,Salem, PY - 2004/11/3/pubmed PY - 2005/2/4/medline PY - 2004/11/3/entrez SP - 484 EP - 91 JF - La Tunisie medicale JO - Tunis Med VL - 82 IS - 6 N2 - Nonalcoholic steatohepatitis is an acquired liver disease, usually metabolic characterised by histologic lesions with steatosis, intralobular necrosis and inflammatory infiltrates. Liver biopsy findings are identical to those seen in alcoholic hepatitis. Nonalcoholic steatohepatitis is increasingly reported in industrial countries because of an increase of the prevalence of obesity and diabetes which are the most common risk factors of this disease. The diagnosis of nonalcoholic steatohepatitis is based on a confrontation between clinical and anatomic data and an exclusion of an excessive intake of alcohol and other hepatic disease. Liver biopsy has a prognosis and histologic benefit especially when there is risk factors of fibrosis. This disease is potentially severe with a potential risk for progression to cirrhosis. Progress in pathogenesis is noted but no definite therapy exist. The aim of this review is to indicate current knowledge for the gravity of nonalcoholic steatohepatitis and its consequence and to understand the pathogenesis to prevent cirrhosis. SN - 0041-4131 UR - https://www.unboundmedicine.com/medline/citation/15517946/[Non_alcoholic_steatohepatitis:_an_emergent_and_potentially_serious_pathology]_ DB - PRIME DP - Unbound Medicine ER -
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