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Effect of anterior capsule polishing on fibrotic capsule opacification: three-year results.
J Cataract Refract Surg. 2004 Nov; 30(11):2322-7.JC

Abstract

PURPOSE

To evaluate the long-term effect of anterior capsule polishing on anterior capsule opacification (ACO) and peripheral fibrotic posterior capsule opacification (PCO).

SETTING

Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.

METHODS

This randomized double-blind study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients received round-edged intraocular lenses (IOLs); 26 received an SI-40 IOL (Advanced Medical Optics Inc.) in both eyes, and 26 received a Silens6 IOL (Domilens) in both eyes. Both IOLs consist of different silicone material and have different haptic angulation. The SI-40 IOL has 13.0 mm open-loop poly(methyl methacrylate) (PMMA) haptics angulated by 10 degrees. The Silens6 IOL has 12.5 mm open-loop PMMA haptics with no angulation. In 1 eye, the anterior capsule was extensively polished. The anterior capsule was left unpolished in the contralateral eye, which acted as a control. Digital slitlamp photographs of the ACO and fibrotic PCO were taken with a standardized technique for 3 years postoperatively. The intensity of ACO was measured objectively (score 0% to 100%) using Adobe Photoshop software. Fibrotic PCO was graded subjectively (score 0 to 4).

RESULTS

The mean ACO was 17% in the polished eyes and 26% in the control eyes (P = .0001). The mean fibrotic PCO score was 0.5 and 1.0, respectively (P = .0007). The mean ACO was 15% in the polished SI-40 eyes and 26% in the control SI-40 eyes (P = .01). It was 19% in the polished Silens6 eyes and 26% in the control Silens6 eyes (P = .003). The mean fibrotic PCO score was 0.4 in the polished SI-40 eyes and 1.1 in the control SI-40 eyes (P = .0006). It was 0.6 in the polished Silens6 eyes and 0.9 in the control Silens6 eyes (P = .08).

CONCLUSIONS

Three years after surgery, eyes in which the anterior capsule was extensively polished had less ACO and fibrotic PCO with both round-edged silicone IOLs. In eyes with Silens6 IOLs, however, the reduction in fibrotic PCO was not significant.

Authors+Show Affiliations

Department of Ophthalmology, Medical University of Vienna, Medical School, Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

15519082

Citation

Sacu, Stefan, et al. "Effect of Anterior Capsule Polishing On Fibrotic Capsule Opacification: Three-year Results." Journal of Cataract and Refractive Surgery, vol. 30, no. 11, 2004, pp. 2322-7.
Sacu S, Menapace R, Wirtitsch M, et al. Effect of anterior capsule polishing on fibrotic capsule opacification: three-year results. J Cataract Refract Surg. 2004;30(11):2322-7.
Sacu, S., Menapace, R., Wirtitsch, M., Buehl, W., Rainer, G., & Findl, O. (2004). Effect of anterior capsule polishing on fibrotic capsule opacification: three-year results. Journal of Cataract and Refractive Surgery, 30(11), 2322-7.
Sacu S, et al. Effect of Anterior Capsule Polishing On Fibrotic Capsule Opacification: Three-year Results. J Cataract Refract Surg. 2004;30(11):2322-7. PubMed PMID: 15519082.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of anterior capsule polishing on fibrotic capsule opacification: three-year results. AU - Sacu,Stefan, AU - Menapace,Rupert, AU - Wirtitsch,Matthias, AU - Buehl,Wolf, AU - Rainer,Georg, AU - Findl,Oliver, PY - 2004/02/24/accepted PY - 2004/11/3/pubmed PY - 2005/1/26/medline PY - 2004/11/3/entrez SP - 2322 EP - 7 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 30 IS - 11 N2 - PURPOSE: To evaluate the long-term effect of anterior capsule polishing on anterior capsule opacification (ACO) and peripheral fibrotic posterior capsule opacification (PCO). SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: This randomized double-blind study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients received round-edged intraocular lenses (IOLs); 26 received an SI-40 IOL (Advanced Medical Optics Inc.) in both eyes, and 26 received a Silens6 IOL (Domilens) in both eyes. Both IOLs consist of different silicone material and have different haptic angulation. The SI-40 IOL has 13.0 mm open-loop poly(methyl methacrylate) (PMMA) haptics angulated by 10 degrees. The Silens6 IOL has 12.5 mm open-loop PMMA haptics with no angulation. In 1 eye, the anterior capsule was extensively polished. The anterior capsule was left unpolished in the contralateral eye, which acted as a control. Digital slitlamp photographs of the ACO and fibrotic PCO were taken with a standardized technique for 3 years postoperatively. The intensity of ACO was measured objectively (score 0% to 100%) using Adobe Photoshop software. Fibrotic PCO was graded subjectively (score 0 to 4). RESULTS: The mean ACO was 17% in the polished eyes and 26% in the control eyes (P = .0001). The mean fibrotic PCO score was 0.5 and 1.0, respectively (P = .0007). The mean ACO was 15% in the polished SI-40 eyes and 26% in the control SI-40 eyes (P = .01). It was 19% in the polished Silens6 eyes and 26% in the control Silens6 eyes (P = .003). The mean fibrotic PCO score was 0.4 in the polished SI-40 eyes and 1.1 in the control SI-40 eyes (P = .0006). It was 0.6 in the polished Silens6 eyes and 0.9 in the control Silens6 eyes (P = .08). CONCLUSIONS: Three years after surgery, eyes in which the anterior capsule was extensively polished had less ACO and fibrotic PCO with both round-edged silicone IOLs. In eyes with Silens6 IOLs, however, the reduction in fibrotic PCO was not significant. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/15519082/Effect_of_anterior_capsule_polishing_on_fibrotic_capsule_opacification:_three_year_results_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886335004004195 DB - PRIME DP - Unbound Medicine ER -