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Diagnosis and management of hemolysis, elevated liver enzymes, and low platelets syndrome.
Clin Perinatol. 2004 Dec; 31(4):807-33, vii.CP

Abstract

Pregnancies complicated by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome require a well-formulated management plan. The development of this syndrome after 34 weeks' gestation or with documentation of maternal or fetal compromise is an indication for delivery. Acute fatty liver of pregnancy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura may present with signs, symptoms, and laboratory abnormalities that may be confused with HELLP syndrome. Thorough investigation is warranted because of the differences in proper management among these various complications of pregnancy. Expectant management in patients with HELLP syndrome remote from term and the use of corticosteroids to improve postpartum maternal outcome remain experimental.

Authors+Show Affiliations

Barton JR
Central Baptist Hospital, Perinatal Diagnostic Center, 1740 Nicholasville Road, Lexington, KY 40503-1499, USA. jbarton@bhsi.com
Sibai BM
No affiliation info available

MeSH

CounselingDiagnosis, DifferentialFemaleHELLP SyndromeHumansLiver Function TestsPlatelet CountPregnancyPregnancy Outcome

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15519429

Citation

Barton, John R., and Baha M. Sibai. "Diagnosis and Management of Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome." Clinics in Perinatology, vol. 31, no. 4, 2004, pp. 807-33, vii.
Barton JR, Sibai BM. Diagnosis and management of hemolysis, elevated liver enzymes, and low platelets syndrome. Clin Perinatol. 2004;31(4):807-33, vii.
Barton, J. R., & Sibai, B. M. (2004). Diagnosis and management of hemolysis, elevated liver enzymes, and low platelets syndrome. Clinics in Perinatology, 31(4), 807-33, vii.
Barton JR, Sibai BM. Diagnosis and Management of Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome. Clin Perinatol. 2004;31(4):807-33, vii. PubMed PMID: 15519429.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis and management of hemolysis, elevated liver enzymes, and low platelets syndrome. AU - Barton,John R, AU - Sibai,Baha M, PY - 2004/11/3/pubmed PY - 2005/1/28/medline PY - 2004/11/3/entrez SP - 807-33, vii JF - Clinics in perinatology JO - Clin Perinatol VL - 31 IS - 4 N2 - Pregnancies complicated by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome require a well-formulated management plan. The development of this syndrome after 34 weeks' gestation or with documentation of maternal or fetal compromise is an indication for delivery. Acute fatty liver of pregnancy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura may present with signs, symptoms, and laboratory abnormalities that may be confused with HELLP syndrome. Thorough investigation is warranted because of the differences in proper management among these various complications of pregnancy. Expectant management in patients with HELLP syndrome remote from term and the use of corticosteroids to improve postpartum maternal outcome remain experimental. SN - 0095-5108 UR - https://www.unboundmedicine.com/medline/citation/15519429/Diagnosis_and_management_of_hemolysis_elevated_liver_enzymes_and_low_platelets_syndrome_ DB - PRIME DP - Unbound Medicine ER -