TY - JOUR T1 - Investigation of the silylation of ephedrines using N-methyl-N-trimethylsilyl-trifluoroacetamide. AU - Forsdahl,Guro, AU - Gmeiner,Günter, PY - 2004/03/02/received PY - 2004/09/01/accepted PY - 2004/11/4/pubmed PY - 2005/3/25/medline PY - 2004/11/4/entrez SP - 201 EP - 8 JF - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences JO - J Chromatogr B Analyt Technol Biomed Life Sci VL - 811 IS - 2 N2 - This paper describes a gas chromatography (GC)--mass spectrometry (MS) method for the simultaneous quantification of ephedrine, pseudoephedrine, cathine, norephedrine and methylephedrine in urine. The sample preparation step includes solid phase extraction and derivatisation with N-methyl-N-trimethylsilyl-trifluoroacetamide (MSTFA). An evaluation of various silylation conditions compatible with screening methods in doping control analysis is presented. The method was found to be well suited for quantification of ephedrines in doping control. SN - 1570-0232 UR - https://www.unboundmedicine.com/medline/citation/15522721/Investigation_of_the_silylation_of_ephedrines_using_N_methyl_N_trimethylsilyl_trifluoroacetamide_ DB - PRIME DP - Unbound Medicine ER -