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Case of recalcitrant necrobiotic xanthogranuloma.
Australas J Dermatol. 2004 Nov; 45(4):213-5.AJ

Abstract

A 53-year-old woman with necrobiotic xanthogranuloma presented as infiltrated eyelid plaques, with later development of arm and thigh lesions. Clinical features, including association with immunoglobulin G-kappa paraprotein, and pathological findings were typical of this disorder. Treatment for 15 months with varying combinations of prednisone and multiple chemotherapeutic agents (melphalan, cyclophosphamide and chlorambucil) has led to minimal or no improvement in the clinical lesions or paraprotein. The case demonstrates some of the difficulties in managing this unusual disorder.

Authors+Show Affiliations

Department of Dermatology, Royal Newcastle Hospital, Newcastle, New South Wales, Australia. jillian_wells@bigpond.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

15527430

Citation

Wells, Jillian, et al. "Case of Recalcitrant Necrobiotic Xanthogranuloma." The Australasian Journal of Dermatology, vol. 45, no. 4, 2004, pp. 213-5.
Wells J, Gillespie R, Zardawi I. Case of recalcitrant necrobiotic xanthogranuloma. Australas J Dermatol. 2004;45(4):213-5.
Wells, J., Gillespie, R., & Zardawi, I. (2004). Case of recalcitrant necrobiotic xanthogranuloma. The Australasian Journal of Dermatology, 45(4), 213-5.
Wells J, Gillespie R, Zardawi I. Case of Recalcitrant Necrobiotic Xanthogranuloma. Australas J Dermatol. 2004;45(4):213-5. PubMed PMID: 15527430.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Case of recalcitrant necrobiotic xanthogranuloma. AU - Wells,Jillian, AU - Gillespie,Rod, AU - Zardawi,Ibrahim, PY - 2004/11/6/pubmed PY - 2004/12/16/medline PY - 2004/11/6/entrez SP - 213 EP - 5 JF - The Australasian journal of dermatology JO - Australas. J. Dermatol. VL - 45 IS - 4 N2 - A 53-year-old woman with necrobiotic xanthogranuloma presented as infiltrated eyelid plaques, with later development of arm and thigh lesions. Clinical features, including association with immunoglobulin G-kappa paraprotein, and pathological findings were typical of this disorder. Treatment for 15 months with varying combinations of prednisone and multiple chemotherapeutic agents (melphalan, cyclophosphamide and chlorambucil) has led to minimal or no improvement in the clinical lesions or paraprotein. The case demonstrates some of the difficulties in managing this unusual disorder. SN - 0004-8380 UR - https://www.unboundmedicine.com/medline/citation/15527430/Case_of_recalcitrant_necrobiotic_xanthogranuloma_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0004-8380&date=2004&volume=45&issue=4&spage=213 DB - PRIME DP - Unbound Medicine ER -