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A clinician's guide to hereditary colon cancer.
Cancer J. 2004 Sep-Oct; 10(5):280-7.CJ

Abstract

Approximately 10% of patients diagnosed with colorectal cancer are at risk for a hereditary form of the disease. At-risk patients can be offered genetic counseling and testing to determine whether they carry a detectable mutation for such a syndrome. If so, this information provides the clinician with valuable data about the patient's risk for other cancers, and what further surveillance and risk reduction options should be incorporated into the management plan. Mutation identification within a family also makes it possible for other family members to learn if they are at risk for the same syndrome. There are many hereditary colorectal cancer syndromes, and the clinician must know what essential information should be elicited from a family history and which patients should be referred for genetic counseling and testing.

Authors+Show Affiliations

From the Yale Cancer Center, Yale University, New Haven, Connecticut 06510, USA. ellen.matloff@yale.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15530254

Citation

Matloff, Ellen T., et al. "A Clinician's Guide to Hereditary Colon Cancer." Cancer Journal (Sudbury, Mass.), vol. 10, no. 5, 2004, pp. 280-7.
Matloff ET, Brierley KL, Chimera CM. A clinician's guide to hereditary colon cancer. Cancer J. 2004;10(5):280-7.
Matloff, E. T., Brierley, K. L., & Chimera, C. M. (2004). A clinician's guide to hereditary colon cancer. Cancer Journal (Sudbury, Mass.), 10(5), 280-7.
Matloff ET, Brierley KL, Chimera CM. A Clinician's Guide to Hereditary Colon Cancer. Cancer J. 2004 Sep-Oct;10(5):280-7. PubMed PMID: 15530254.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A clinician's guide to hereditary colon cancer. AU - Matloff,Ellen T, AU - Brierley,Karina L, AU - Chimera,Christina M, PY - 2004/11/9/pubmed PY - 2005/3/18/medline PY - 2004/11/9/entrez SP - 280 EP - 7 JF - Cancer journal (Sudbury, Mass.) JO - Cancer J VL - 10 IS - 5 N2 - Approximately 10% of patients diagnosed with colorectal cancer are at risk for a hereditary form of the disease. At-risk patients can be offered genetic counseling and testing to determine whether they carry a detectable mutation for such a syndrome. If so, this information provides the clinician with valuable data about the patient's risk for other cancers, and what further surveillance and risk reduction options should be incorporated into the management plan. Mutation identification within a family also makes it possible for other family members to learn if they are at risk for the same syndrome. There are many hereditary colorectal cancer syndromes, and the clinician must know what essential information should be elicited from a family history and which patients should be referred for genetic counseling and testing. SN - 1528-9117 UR - https://www.unboundmedicine.com/medline/citation/15530254/A_clinician's_guide_to_hereditary_colon_cancer_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=15530254.ui DB - PRIME DP - Unbound Medicine ER -