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[The role of esophageal sphincter tonus and of gastric motility in the extent of reflux esophagitis].
Minerva Chir. 1992 Jan; 47(1-2):11-7.MC

Abstract

Thirty-two patients with symptomatic gastroesophageal reflux disease were investigated by esophagogastroduodenoscopy, 24 h pH monitoring, esophageal manometry and measurement of gastric emptying of solids, in order to elucidate the relative importance of lower esophageal sphincter tone, amount of acid reflux and gastric emptying on the degree of esophagitis. The mechanical competency of lower esophageal sphincter was significantly deranged in patients with moderate/severe esophagitis than in patients with mild esophagitis. The gastric emptying time was significantly delayed in patients with moderate/severe esophagitis than in patients with mild esophagitis. No relationship was observed between amount of acid reflux, lower esophageal sphincter function and gastric emptying time. Our results suggest that resting pressure of lower esophageal sphincter and the gastric motor function play a major role in severity of reflux esophagitis.

Authors+Show Affiliations

Cattedra di Chirurgia Generale e di Pronto Soccorso, Università degli Studi di Messina.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ita

PubMed ID

1553047

Citation

Cogliandolo, A, et al. "[The Role of Esophageal Sphincter Tonus and of Gastric Motility in the Extent of Reflux Esophagitis]." Minerva Chirurgica, vol. 47, no. 1-2, 1992, pp. 11-7.
Cogliandolo A, Gulino FM, Pustorino S, et al. [The role of esophageal sphincter tonus and of gastric motility in the extent of reflux esophagitis]. Minerva Chir. 1992;47(1-2):11-7.
Cogliandolo, A., Gulino, F. M., Pustorino, S., Migliorato, D., Bottari, M., Saitta, F. P., & Micali, B. (1992). [The role of esophageal sphincter tonus and of gastric motility in the extent of reflux esophagitis]. Minerva Chirurgica, 47(1-2), 11-7.
Cogliandolo A, et al. [The Role of Esophageal Sphincter Tonus and of Gastric Motility in the Extent of Reflux Esophagitis]. Minerva Chir. 1992;47(1-2):11-7. PubMed PMID: 1553047.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The role of esophageal sphincter tonus and of gastric motility in the extent of reflux esophagitis]. AU - Cogliandolo,A, AU - Gulino,F M, AU - Pustorino,S, AU - Migliorato,D, AU - Bottari,M, AU - Saitta,F P, AU - Micali,B, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 11 EP - 7 JF - Minerva chirurgica JO - Minerva Chir VL - 47 IS - 1-2 N2 - Thirty-two patients with symptomatic gastroesophageal reflux disease were investigated by esophagogastroduodenoscopy, 24 h pH monitoring, esophageal manometry and measurement of gastric emptying of solids, in order to elucidate the relative importance of lower esophageal sphincter tone, amount of acid reflux and gastric emptying on the degree of esophagitis. The mechanical competency of lower esophageal sphincter was significantly deranged in patients with moderate/severe esophagitis than in patients with mild esophagitis. The gastric emptying time was significantly delayed in patients with moderate/severe esophagitis than in patients with mild esophagitis. No relationship was observed between amount of acid reflux, lower esophageal sphincter function and gastric emptying time. Our results suggest that resting pressure of lower esophageal sphincter and the gastric motor function play a major role in severity of reflux esophagitis. SN - 0026-4733 UR - https://www.unboundmedicine.com/medline/citation/1553047/[The_role_of_esophageal_sphincter_tonus_and_of_gastric_motility_in_the_extent_of_reflux_esophagitis]_ DB - PRIME DP - Unbound Medicine ER -