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Antimicrobial activity and chemical composition of the essential oil of Nepeta crispa Willd. from Iran.
Z Naturforsch C J Biosci. 2004 Sep-Oct; 59(9-10):653-6.ZN

Abstract

The composition and antimicrobial activity of the essential oil of Nepeta crispa Willd., an endemic species from Iran, was studied. The oil was obtained from the aerial parts of the plant and analyzed by GC and GC/MS. Twenty-three compounds, accounting for 99.8% of the total oil, were identified. The main constituents were 1,8-cineol (47.9%) and 4aalpha,7alpha,7abetanepetalactone (20.3%). The antimicrobial activity of essential oil of N. crispa was tested against seven gram-negative or gram-positive bacteria and four fungi. The results of the bioassays showed the interesting antimicrobial activity, in which the gram-positive bacteria, Bacillus subtilis and Staphylococcus aureus, were the most sensitive to the oil. Also, the oil exhibited a remarkable antifungal activity against all the tested fungi.

Authors+Show Affiliations

Department of Biology, Medicinal Plants Research Institute, Shahid Beheshti University, Evin, P. O. Box 198 35-3 89, Tehran, Iran. a-sonboli@sbu.ac.irNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15540597

Citation

Sonboli, Ali, et al. "Antimicrobial Activity and Chemical Composition of the Essential Oil of Nepeta Crispa Willd. From Iran." Zeitschrift Fur Naturforschung. C, Journal of Biosciences, vol. 59, no. 9-10, 2004, pp. 653-6.
Sonboli A, Salehi P, Yousefzadi M. Antimicrobial activity and chemical composition of the essential oil of Nepeta crispa Willd. from Iran. Z Naturforsch C J Biosci. 2004;59(9-10):653-6.
Sonboli, A., Salehi, P., & Yousefzadi, M. (2004). Antimicrobial activity and chemical composition of the essential oil of Nepeta crispa Willd. from Iran. Zeitschrift Fur Naturforschung. C, Journal of Biosciences, 59(9-10), 653-6.
Sonboli A, Salehi P, Yousefzadi M. Antimicrobial Activity and Chemical Composition of the Essential Oil of Nepeta Crispa Willd. From Iran. Z Naturforsch C J Biosci. 2004 Sep-Oct;59(9-10):653-6. PubMed PMID: 15540597.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial activity and chemical composition of the essential oil of Nepeta crispa Willd. from Iran. AU - Sonboli,Ali, AU - Salehi,Peyman, AU - Yousefzadi,Morteza, PY - 2004/11/16/pubmed PY - 2004/12/16/medline PY - 2004/11/16/entrez SP - 653 EP - 6 JF - Zeitschrift fur Naturforschung. C, Journal of biosciences JO - Z Naturforsch C J Biosci VL - 59 IS - 9-10 N2 - The composition and antimicrobial activity of the essential oil of Nepeta crispa Willd., an endemic species from Iran, was studied. The oil was obtained from the aerial parts of the plant and analyzed by GC and GC/MS. Twenty-three compounds, accounting for 99.8% of the total oil, were identified. The main constituents were 1,8-cineol (47.9%) and 4aalpha,7alpha,7abetanepetalactone (20.3%). The antimicrobial activity of essential oil of N. crispa was tested against seven gram-negative or gram-positive bacteria and four fungi. The results of the bioassays showed the interesting antimicrobial activity, in which the gram-positive bacteria, Bacillus subtilis and Staphylococcus aureus, were the most sensitive to the oil. Also, the oil exhibited a remarkable antifungal activity against all the tested fungi. SN - 0939-5075 UR - https://www.unboundmedicine.com/medline/citation/15540597/Antimicrobial_activity_and_chemical_composition_of_the_essential_oil_of_Nepeta_crispa_Willd__from_Iran_ L2 - https://www.degruyter.com/document/doi/10.1515/znc-2004-9-1008 DB - PRIME DP - Unbound Medicine ER -