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Small fiber neuropathy: a common and important clinical disorder.
J Neurol Sci. 2004 Dec 15; 227(1):119-30.JN

Abstract

Small fiber neuropathy (SFN) is a neuropathy selectively involving small diameter myelinated and unmyelinated nerve fibers. Interest in this disorder has considerably increased during the past few years. It is often idiopathic and typically presents with peripheral pain and/or symptoms of autonomic dysfunction. Diagnosis is made on the basis of the clinical features, normal nerve conduction studies (NCS) and abnormal specialized tests of small nerve fibers. Among others, these tests include assessment of epidermal nerve fiber density, temperature sensation tests for sensory fibers and sudomotor and cardiovagal testing (QSART) for autonomic fibers. Unless an underlying disease is identified, treatment is usually symptomatic and directed towards alleviation of neuropathic pain.

Authors+Show Affiliations

Department of Clinical Neurophysiology, Maastricht University Hospital, Maastricht, The Netherlands. elske.hoitsma@wanadoo.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15546602

Citation

Hoitsma, E, et al. "Small Fiber Neuropathy: a Common and Important Clinical Disorder." Journal of the Neurological Sciences, vol. 227, no. 1, 2004, pp. 119-30.
Hoitsma E, Reulen JP, de Baets M, et al. Small fiber neuropathy: a common and important clinical disorder. J Neurol Sci. 2004;227(1):119-30.
Hoitsma, E., Reulen, J. P., de Baets, M., Drent, M., Spaans, F., & Faber, C. G. (2004). Small fiber neuropathy: a common and important clinical disorder. Journal of the Neurological Sciences, 227(1), 119-30.
Hoitsma E, et al. Small Fiber Neuropathy: a Common and Important Clinical Disorder. J Neurol Sci. 2004 Dec 15;227(1):119-30. PubMed PMID: 15546602.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Small fiber neuropathy: a common and important clinical disorder. AU - Hoitsma,E, AU - Reulen,J P H, AU - de Baets,M, AU - Drent,M, AU - Spaans,F, AU - Faber,C G, PY - 2004/06/02/received PY - 2004/08/27/revised PY - 2004/08/30/accepted PY - 2004/11/18/pubmed PY - 2005/2/16/medline PY - 2004/11/18/entrez SP - 119 EP - 30 JF - Journal of the neurological sciences JO - J Neurol Sci VL - 227 IS - 1 N2 - Small fiber neuropathy (SFN) is a neuropathy selectively involving small diameter myelinated and unmyelinated nerve fibers. Interest in this disorder has considerably increased during the past few years. It is often idiopathic and typically presents with peripheral pain and/or symptoms of autonomic dysfunction. Diagnosis is made on the basis of the clinical features, normal nerve conduction studies (NCS) and abnormal specialized tests of small nerve fibers. Among others, these tests include assessment of epidermal nerve fiber density, temperature sensation tests for sensory fibers and sudomotor and cardiovagal testing (QSART) for autonomic fibers. Unless an underlying disease is identified, treatment is usually symptomatic and directed towards alleviation of neuropathic pain. SN - 0022-510X UR - https://www.unboundmedicine.com/medline/citation/15546602/Small_fiber_neuropathy:_a_common_and_important_clinical_disorder_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-510X(04)00321-1 DB - PRIME DP - Unbound Medicine ER -