Tags

Type your tag names separated by a space and hit enter

Export of the outer membrane lipoprotein is defective in secD, secE, and secF mutants of Escherichia coli.
J Bacteriol. 1992 Apr; 174(8):2511-6.JB

Abstract

The export of major outer membrane lipoprotein has been found to be affected in secD, secE, and secF mutants of Escherichia coli, which are defective in protein export in general. After a shift to the nonpermissive temperature, the kinetics of accumulation of prolipoprotein and pre-OmpA protein was indistinguishable from that of pre-OmpA protein accumulation in the secD and secF mutants but different in the secE mutant. The prolipoprotein accumulated in the secD, secE, and secF mutants at the nonpermissive temperature was not modified with glyceride. We conclude from these results and those of previous studies that the export of lipoprotein requires all common sec gene products except the SecB protein, i.e., the SecA, SecD, SecE, SecF, and SecY proteins.

Authors+Show Affiliations

Department of Microbiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799.No affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

1556071

Citation

Sugai, M, and H C. Wu. "Export of the Outer Membrane Lipoprotein Is Defective in secD, secE, and secF Mutants of Escherichia Coli." Journal of Bacteriology, vol. 174, no. 8, 1992, pp. 2511-6.
Sugai M, Wu HC. Export of the outer membrane lipoprotein is defective in secD, secE, and secF mutants of Escherichia coli. J Bacteriol. 1992;174(8):2511-6.
Sugai, M., & Wu, H. C. (1992). Export of the outer membrane lipoprotein is defective in secD, secE, and secF mutants of Escherichia coli. Journal of Bacteriology, 174(8), 2511-6.
Sugai M, Wu HC. Export of the Outer Membrane Lipoprotein Is Defective in secD, secE, and secF Mutants of Escherichia Coli. J Bacteriol. 1992;174(8):2511-6. PubMed PMID: 1556071.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Export of the outer membrane lipoprotein is defective in secD, secE, and secF mutants of Escherichia coli. AU - Sugai,M, AU - Wu,H C, PY - 1992/4/1/pubmed PY - 1992/4/1/medline PY - 1992/4/1/entrez SP - 2511 EP - 6 JF - Journal of bacteriology JO - J. Bacteriol. VL - 174 IS - 8 N2 - The export of major outer membrane lipoprotein has been found to be affected in secD, secE, and secF mutants of Escherichia coli, which are defective in protein export in general. After a shift to the nonpermissive temperature, the kinetics of accumulation of prolipoprotein and pre-OmpA protein was indistinguishable from that of pre-OmpA protein accumulation in the secD and secF mutants but different in the secE mutant. The prolipoprotein accumulated in the secD, secE, and secF mutants at the nonpermissive temperature was not modified with glyceride. We conclude from these results and those of previous studies that the export of lipoprotein requires all common sec gene products except the SecB protein, i.e., the SecA, SecD, SecE, SecF, and SecY proteins. SN - 0021-9193 UR - https://www.unboundmedicine.com/medline/citation/1556071/Export_of_the_outer_membrane_lipoprotein_is_defective_in_secD_secE_and_secF_mutants_of_Escherichia_coli_ L2 - http://jb.asm.org/cgi/pmidlookup?view=long&pmid=1556071 DB - PRIME DP - Unbound Medicine ER -