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Inter- and intra-individual variability in performance near the circadian nadir during sleep deprivation.
J Sleep Res. 2004 Dec; 13(4):305-15.JS

Abstract

The study purpose was to assess inter- and intra-individual variability in neurobehavioral function near the circadian nadir during sleep deprivation and conduct exploratory factor analyses to assess relationships among alertness and performance measures during sleep deprivation. Twenty-five healthy individuals (16 females) aged 18-25 years participated. Participants were sleep deprived for two nights under controlled laboratory conditions using a modified constant routine procedure. A comprehensive battery of neurobehavioral performance tests, subjective sleepiness (SSS), and objective alertness (MWT) were assessed. Seventeen of the 22 neurobehavioral measures were impaired by sleep deprivation (all P < 0.01). The use of multiple neurobehavioral performance measures revealed impairments for all individuals during sleep deprivation. However, sleep deprivation effects were task dependent within and between individuals. Gender contributed minimally to inter-individual variability in performance. Exploratory factor analysis reduced the 22 measures to seven independent factors. Our findings indicate that no individual was especially vulnerable or resistant to the performance impairing effects of sleep deprivation. Instead, inter- and intra-individual variability in performance during sleep deprivation was task dependent. The finding that subjective sleepiness and objective alertness were not related to any performance measure during sleep deprivation suggests that these measures may assess independent brain functions.

Authors+Show Affiliations

Frey DJ
Sleep and Chronobiology Laboratory, Department of Integrative Physiology and the Center for Neuroscience, University of Colorado at Boulder, Boulder, CO 80309, USA.
Badia P
No affiliation info available
Wright KP
No affiliation info available

MeSH

AdolescentAdultArousalBrainChronobiology DisordersCognitionDisorders of Excessive SomnolenceElectroencephalographyFactor Analysis, StatisticalFemaleHumansMaleMemory, Short-TermNeuropsychological TestsPolysomnographySeverity of Illness IndexSleep DeprivationSpace PerceptionWakefulness

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15560765

Citation

Frey, Danielle J., et al. "Inter- and Intra-individual Variability in Performance Near the Circadian Nadir During Sleep Deprivation." Journal of Sleep Research, vol. 13, no. 4, 2004, pp. 305-15.
Frey DJ, Badia P, Wright KP. Inter- and intra-individual variability in performance near the circadian nadir during sleep deprivation. J Sleep Res. 2004;13(4):305-15.
Frey, D. J., Badia, P., & Wright, K. P. (2004). Inter- and intra-individual variability in performance near the circadian nadir during sleep deprivation. Journal of Sleep Research, 13(4), 305-15.
Frey DJ, Badia P, Wright KP. Inter- and Intra-individual Variability in Performance Near the Circadian Nadir During Sleep Deprivation. J Sleep Res. 2004;13(4):305-15. PubMed PMID: 15560765.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Inter- and intra-individual variability in performance near the circadian nadir during sleep deprivation. AU - Frey,Danielle J, AU - Badia,Pietro, AU - Wright,Kenneth P,Jr PY - 2004/11/25/pubmed PY - 2005/3/25/medline PY - 2004/11/25/entrez SP - 305 EP - 15 JF - Journal of sleep research JO - J Sleep Res VL - 13 IS - 4 N2 - The study purpose was to assess inter- and intra-individual variability in neurobehavioral function near the circadian nadir during sleep deprivation and conduct exploratory factor analyses to assess relationships among alertness and performance measures during sleep deprivation. Twenty-five healthy individuals (16 females) aged 18-25 years participated. Participants were sleep deprived for two nights under controlled laboratory conditions using a modified constant routine procedure. A comprehensive battery of neurobehavioral performance tests, subjective sleepiness (SSS), and objective alertness (MWT) were assessed. Seventeen of the 22 neurobehavioral measures were impaired by sleep deprivation (all P < 0.01). The use of multiple neurobehavioral performance measures revealed impairments for all individuals during sleep deprivation. However, sleep deprivation effects were task dependent within and between individuals. Gender contributed minimally to inter-individual variability in performance. Exploratory factor analysis reduced the 22 measures to seven independent factors. Our findings indicate that no individual was especially vulnerable or resistant to the performance impairing effects of sleep deprivation. Instead, inter- and intra-individual variability in performance during sleep deprivation was task dependent. The finding that subjective sleepiness and objective alertness were not related to any performance measure during sleep deprivation suggests that these measures may assess independent brain functions. SN - 0962-1105 UR - https://www.unboundmedicine.com/medline/citation/15560765/Inter__and_intra_individual_variability_in_performance_near_the_circadian_nadir_during_sleep_deprivation_ DB - PRIME DP - Unbound Medicine ER -