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Alteration of antibodies against the fifth-stage larvae and changes in brain magnetic resonance images in experimentally infected rabbits with Angiostrongylus cantonensis.
J Parasitol. 2004 Oct; 90(5):1193-6.JP

Abstract

Magnetic resonance (MR) imaging has been suggested to be helpful in delineating the lesions during the acute phase of angiostrongyliasis caused by Angiostrongylus cantonensis. In this study, antibody titers in serum samples of 3 rabbits were determined by enzyme-linked immunosorbent assay, and brain MR images were obtained from 6 rabbits. The antibody titer elevated rapidly in the first 4 wk postinfection (PI) before reaching a plateau. However, suspicious changes in brain MR images near the left lateral ventricle and hippocampus were found only in 1 rabbit on day 28 PI. These findings indicate that immunologic responses in the central nervous system at the early stage of angiostrongyliasis are not sufficient to be observed by image studies.

Authors+Show Affiliations

Department of Parasitology, School of Medicine, Chang-Gung University, Kueisan, Taoyuan, Taiwan.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15562631

Citation

Wang, Lian-Chen, and Yung-Liang Wan. "Alteration of Antibodies Against the Fifth-stage Larvae and Changes in Brain Magnetic Resonance Images in Experimentally Infected Rabbits With Angiostrongylus Cantonensis." The Journal of Parasitology, vol. 90, no. 5, 2004, pp. 1193-6.
Wang LC, Wan YL. Alteration of antibodies against the fifth-stage larvae and changes in brain magnetic resonance images in experimentally infected rabbits with Angiostrongylus cantonensis. J Parasitol. 2004;90(5):1193-6.
Wang, L. C., & Wan, Y. L. (2004). Alteration of antibodies against the fifth-stage larvae and changes in brain magnetic resonance images in experimentally infected rabbits with Angiostrongylus cantonensis. The Journal of Parasitology, 90(5), 1193-6.
Wang LC, Wan YL. Alteration of Antibodies Against the Fifth-stage Larvae and Changes in Brain Magnetic Resonance Images in Experimentally Infected Rabbits With Angiostrongylus Cantonensis. J Parasitol. 2004;90(5):1193-6. PubMed PMID: 15562631.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alteration of antibodies against the fifth-stage larvae and changes in brain magnetic resonance images in experimentally infected rabbits with Angiostrongylus cantonensis. AU - Wang,Lian-Chen, AU - Wan,Yung-Liang, PY - 2004/11/26/pubmed PY - 2004/12/16/medline PY - 2004/11/26/entrez SP - 1193 EP - 6 JF - The Journal of parasitology JO - J Parasitol VL - 90 IS - 5 N2 - Magnetic resonance (MR) imaging has been suggested to be helpful in delineating the lesions during the acute phase of angiostrongyliasis caused by Angiostrongylus cantonensis. In this study, antibody titers in serum samples of 3 rabbits were determined by enzyme-linked immunosorbent assay, and brain MR images were obtained from 6 rabbits. The antibody titer elevated rapidly in the first 4 wk postinfection (PI) before reaching a plateau. However, suspicious changes in brain MR images near the left lateral ventricle and hippocampus were found only in 1 rabbit on day 28 PI. These findings indicate that immunologic responses in the central nervous system at the early stage of angiostrongyliasis are not sufficient to be observed by image studies. SN - 0022-3395 UR - https://www.unboundmedicine.com/medline/citation/15562631/Alteration_of_antibodies_against_the_fifth_stage_larvae_and_changes_in_brain_magnetic_resonance_images_in_experimentally_infected_rabbits_with_Angiostrongylus_cantonensis_ L2 - https://doi.org/10.1645/GE-319R DB - PRIME DP - Unbound Medicine ER -