TY - JOUR T1 - The role of sex hormones in headache. A1 - Silberstein,S D, PY - 1992/3/1/pubmed PY - 1992/3/1/medline PY - 1992/3/1/entrez KW - Alkaloids KW - Americas KW - Analgesia KW - Biology KW - Central Nervous System KW - Contraception KW - Contraceptive Methods KW - Developed Countries KW - Diseases KW - Dysmenorrhea KW - Endocrine System KW - Ergot Alkaloids KW - Estrogens KW - Family Planning KW - Gonadotropins KW - Headache KW - Hormones KW - Hypothalamus KW - Ingredients And Chemicals KW - Literature Review KW - Menarche KW - Menopause KW - Menstrual Cycle KW - Menstruation KW - Menstruation Disorders KW - Migraine KW - North America KW - Northern America KW - Oral Contraceptives KW - Organic Chemicals KW - Physiology KW - Pituitary Hormones KW - Pregnancy KW - Prolactin KW - Prostaglandins KW - Reproduction KW - Serotonin KW - Signs And Symptoms KW - Treatment KW - United States KW - Vascular Diseases SP - 37 EP - 42 JF - Neurology JO - Neurology VL - 42 IS - 3 Suppl 2 N2 - Changes in estrogen levels at menarche, menstruation, pregnancy, and menopause may trigger or change the prevalence of migraine. The fall in estrogen that occurs with menstruation is the trigger for menstrual migraine, whereas the sustained high estrogen levels during pregnancy frequently result in headache relief. Estrogen produces changes in prostaglandins, hypothalmic opioids, and prolactin secretion, which may in part account for genesis of headache. The treatment of menstrual migraine and migraine associated with menopause and the use of oral contraceptives is discussed, focusing on standard headache treatment and hormonal manipulation. SN - 0028-3878 UR - https://www.unboundmedicine.com/medline/citation/1557190/The_role_of_sex_hormones_in_headache_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=1557190.ui DB - PRIME DP - Unbound Medicine ER -