Efficient synthesis of alkynylsilyl ethers and silaketals via base-induced alkynylsilane alcoholysis.J Org Chem. 2004 Dec 10; 69(25):8967-70.JO
The efficient silylation of alcohols with di- and trialkynylsilanes was achieved under base-catalyzed conditions to afford alkynyl silyl ethers and symmetrical alkynyl silaketals in good yield. A selective alcoholysis of dialkynyl silyl ethers to mixed silaketals was also demonstrated. These products served as substrates for enyne ring-closing metathesis and, consequently, as precursors to stereochemically defined 1,3-dienes.