Tags

Type your tag names separated by a space and hit enter

Lack of association of heart rate variability parameters with head-up tilt-test responses in patients with syncope.
Indian Heart J. 2004 May-Jun; 56(3):229-31.IH

Abstract

BACKGROUND

Neurocardiogenic syncope is the most common type of syncope. Head-up tilt testing is the investigation of choice for diagnosis of patients with neurocardiogenic syncope. In this study, we aimed to findout any association between heart rate variability parameters and type of tilt-test response in patients with syncope.

METHODS AND RESULTS

Forty-nine cases with unexplained syncopal attacks were enrolled into our study and were grouped according to the tilt-test responses. Tilt test was performed in all patients after excluding other causes of syncope. In case of a negative basal tilt-testing, pharmacological tilt testing was performed after 30 min of 5 mg sublingual isosorbide dinitrate. Holter monitoring was done from the beginning of tilt testing upto two hours post-procedure. The heart rate variability parameters analyzed were the mean of all coupling intervals between normal beats, the standard deviation about the mean of all coupling intervals between normal beats, the mean of all 5-min standard deviations of mean of all coupling intervals between normal beats, the proportion of adjacent normal R-R intervals differing by > 50 ms, the root mean square of the difference between successive RRs, and the standard deviation of 5-min mean of all coupling intervals between normal beats and ratio between low and high frequencies.

CONCLUSIONS

In 35 patients, the tilt-test was positive, 16 were cardioinhibitor type (Group 1), four cases had a vasodepressor type response (Group 2) and 15 were mixed type (Group 3). Fourteen patients had a negative test result. The heart rate variability measures did not significantly differ among the study groups. The heart rate variability measures were compared between the tilt-test negative (Group 4) and the tilt-test positive groups (Groups 1, 2 and 3) and no statistically significant difference was found.

Authors+Show Affiliations

Baran I
Department of Cardiology, Uludağ University School of Medicine, Turkey.
Kaderli AA
No affiliation info available
Ozdemir B
No affiliation info available
Gemici K
No affiliation info available
Ekbul A
No affiliation info available
Güllülü S
No affiliation info available
Aydinlar A
No affiliation info available
Cordan J
No affiliation info available

MeSH

AdultElectrocardiography, AmbulatoryFemaleHeart RateHumansMaleMiddle AgedPostureSyncope, VasovagalTilt-Table Test

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15584566

Citation

Baran, Ibrahim, et al. "Lack of Association of Heart Rate Variability Parameters With Head-up Tilt-test Responses in Patients With Syncope." Indian Heart Journal, vol. 56, no. 3, 2004, pp. 229-31.
Baran I, Kaderli AA, Ozdemir B, et al. Lack of association of heart rate variability parameters with head-up tilt-test responses in patients with syncope. Indian Heart J. 2004;56(3):229-31.
Baran, I., Kaderli, A. A., Ozdemir, B., Gemici, K., Ekbul, A., Güllülü, S., Aydinlar, A., & Cordan, J. (2004). Lack of association of heart rate variability parameters with head-up tilt-test responses in patients with syncope. Indian Heart Journal, 56(3), 229-31.
Baran I, et al. Lack of Association of Heart Rate Variability Parameters With Head-up Tilt-test Responses in Patients With Syncope. Indian Heart J. 2004 May-Jun;56(3):229-31. PubMed PMID: 15584566.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lack of association of heart rate variability parameters with head-up tilt-test responses in patients with syncope. AU - Baran,Ibrahim, AU - Kaderli,Aysel Aydin, AU - Ozdemir,Bülent, AU - Gemici,Kani, AU - Ekbul,Adem, AU - Güllülü,Sümeyye, AU - Aydinlar,Ali, AU - Cordan,Jale, PY - 2004/12/9/pubmed PY - 2005/2/11/medline PY - 2004/12/9/entrez SP - 229 EP - 31 JF - Indian heart journal JO - Indian Heart J VL - 56 IS - 3 N2 - BACKGROUND: Neurocardiogenic syncope is the most common type of syncope. Head-up tilt testing is the investigation of choice for diagnosis of patients with neurocardiogenic syncope. In this study, we aimed to findout any association between heart rate variability parameters and type of tilt-test response in patients with syncope. METHODS AND RESULTS: Forty-nine cases with unexplained syncopal attacks were enrolled into our study and were grouped according to the tilt-test responses. Tilt test was performed in all patients after excluding other causes of syncope. In case of a negative basal tilt-testing, pharmacological tilt testing was performed after 30 min of 5 mg sublingual isosorbide dinitrate. Holter monitoring was done from the beginning of tilt testing upto two hours post-procedure. The heart rate variability parameters analyzed were the mean of all coupling intervals between normal beats, the standard deviation about the mean of all coupling intervals between normal beats, the mean of all 5-min standard deviations of mean of all coupling intervals between normal beats, the proportion of adjacent normal R-R intervals differing by > 50 ms, the root mean square of the difference between successive RRs, and the standard deviation of 5-min mean of all coupling intervals between normal beats and ratio between low and high frequencies. CONCLUSIONS: In 35 patients, the tilt-test was positive, 16 were cardioinhibitor type (Group 1), four cases had a vasodepressor type response (Group 2) and 15 were mixed type (Group 3). Fourteen patients had a negative test result. The heart rate variability measures did not significantly differ among the study groups. The heart rate variability measures were compared between the tilt-test negative (Group 4) and the tilt-test positive groups (Groups 1, 2 and 3) and no statistically significant difference was found. SN - 0019-4832 UR - https://www.unboundmedicine.com/medline/citation/15584566/Lack_of_association_of_heart_rate_variability_parameters_with_head_up_tilt_test_responses_in_patients_with_syncope_ DB - PRIME DP - Unbound Medicine ER -