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A bedside dipstick method to detect Plasmodium falciparum.
Indian Pediatr. 2004 Nov; 41(11):1148-51.IP

Abstract

We conducted this study to determine efficacy of Parasight-F (an HRP-II antigen dipstick method to detect P. Falciparum) in children. A total of 30 children were enrolled in the age group of 2 months to 12 years whose peripheral smear showed asexual forms of Plasmodium falciparum. All patients were tested for presence of HRP-II antigen of Plasmodium falciparum in their blood by the Parasight-F dipstick test by either an EDTA sample or a finger prick blood sample. The sensitivity of Parasight-F was 83.3 % However, the sensitivity of Parasight-F to detect Plasmodium Falciparum in case of mixed Plasmodium (Vivax + Falciparum) infection was only 25 %. Also, all patients less than 6 months of age had a negative Parasight-F test. Parasitic index, prior treatment with antimalarials or severity of Falciparum malaria have no effect on the sensitivity of Parasight-F test. We conclude that Parasight-F is an effective tool for diagnosis of Plasmoduim falciparum malaria in children.

Authors+Show Affiliations

Shah I
Department of Pediatrics, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai-400012, India. irashah86@hotmail.com
Deshmukh CT
No affiliation info available

MeSH

AnimalsAntigens, ProtozoanChildChild, PreschoolHumansInfantMalariaPlasmodium falciparumPoint-of-Care SystemsProteinsSensitivity and Specificity

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15591666

Citation

Shah, Ira, and C T. Deshmukh. "A Bedside Dipstick Method to Detect Plasmodium Falciparum." Indian Pediatrics, vol. 41, no. 11, 2004, pp. 1148-51.
Shah I, Deshmukh CT. A bedside dipstick method to detect Plasmodium falciparum. Indian Pediatr. 2004;41(11):1148-51.
Shah, I., & Deshmukh, C. T. (2004). A bedside dipstick method to detect Plasmodium falciparum. Indian Pediatrics, 41(11), 1148-51.
Shah I, Deshmukh CT. A Bedside Dipstick Method to Detect Plasmodium Falciparum. Indian Pediatr. 2004;41(11):1148-51. PubMed PMID: 15591666.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A bedside dipstick method to detect Plasmodium falciparum. AU - Shah,Ira, AU - Deshmukh,C T, PY - 2004/12/14/pubmed PY - 2006/9/29/medline PY - 2004/12/14/entrez SP - 1148 EP - 51 JF - Indian pediatrics JO - Indian Pediatr VL - 41 IS - 11 N2 - We conducted this study to determine efficacy of Parasight-F (an HRP-II antigen dipstick method to detect P. Falciparum) in children. A total of 30 children were enrolled in the age group of 2 months to 12 years whose peripheral smear showed asexual forms of Plasmodium falciparum. All patients were tested for presence of HRP-II antigen of Plasmodium falciparum in their blood by the Parasight-F dipstick test by either an EDTA sample or a finger prick blood sample. The sensitivity of Parasight-F was 83.3 % However, the sensitivity of Parasight-F to detect Plasmodium Falciparum in case of mixed Plasmodium (Vivax + Falciparum) infection was only 25 %. Also, all patients less than 6 months of age had a negative Parasight-F test. Parasitic index, prior treatment with antimalarials or severity of Falciparum malaria have no effect on the sensitivity of Parasight-F test. We conclude that Parasight-F is an effective tool for diagnosis of Plasmoduim falciparum malaria in children. SN - 0019-6061 UR - https://www.unboundmedicine.com/medline/citation/15591666/A_bedside_dipstick_method_to_detect_Plasmodium_falciparum_ DB - PRIME DP - Unbound Medicine ER -