Tags

Type your tag names separated by a space and hit enter

Mild elevation of fasting plasma glucose is a strong risk factor for postoperative complications in gastric bypass patients.

Abstract

BACKGROUND

Bariatric surgery may be associated with surgical complications. The aim of the study was to identify significant risk factors for postoperative complications in patients undergoing Roux-en-Y gastric bypass (RYGBP).

METHODS

The study consisted of 75 consecutive patients undergoing RYGBP. Full medical examination was performed, and the following parameters were assessed in the fasting state: plasma glucose, insulin, leptin, serum lipids, liver function tests, and lipoprotein Lp(a). All subjects had oral 75 g glucose tolerance test before the surgery. All complications occurring within 6 months after the RYGBP were recorded. The patients were divided into Group 1 - patients in whom complications occurred, and Group 2 - patients with no complications in the 6-month period.

RESULTS

Postoperative complications occurred in 16 patients (wound infection, hernia, splenic injury, gastro-jejunal obstruction, duodenal ulcer, lower limb deep vein thrombosis). 3 significant risk factors for postoperative complications within 6 months after gastric bypass were found: 1) fasting plasma glucose >/= 6.0 mmol/l (OR 11.0; 95% confidence interval (CI) 2.1-77.3), 2) age >/=40 years (OR 5.89, 95% CI 1.35-29.4), and 3) BMI >/=45 kg/m(2) (OR 4.1, 95% CI 1.04-17.2).

CONCLUSION

RYGBP is associated with increased risk of developing early postoperative complications in subjects with even slightly elevated fasting plasma glucose, age >/=40 and BMI >/=45 kg/m(2).

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Diabetology and Metabolic Diseases, Medical University of Lodz, Lodz, Poland. leszek.czupryniak@dtu.ox.ac.uk

    , ,

    Source

    Obesity surgery 14:10 pg 1393-7

    MeSH

    Adult
    Anastomosis, Roux-en-Y
    Biomarkers
    Blood Glucose
    Body Mass Index
    Case-Control Studies
    Cohort Studies
    Confidence Intervals
    Female
    Gastric Bypass
    Glucose Tolerance Test
    Humans
    Laparoscopy
    Male
    Middle Aged
    Multivariate Analysis
    Obesity, Morbid
    Odds Ratio
    Postoperative Complications
    Predictive Value of Tests
    Prognosis
    Risk Assessment
    Statistics, Nonparametric

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    15603657

    Citation

    Czupryniak, Leszek, et al. "Mild Elevation of Fasting Plasma Glucose Is a Strong Risk Factor for Postoperative Complications in Gastric Bypass Patients." Obesity Surgery, vol. 14, no. 10, 2004, pp. 1393-7.
    Czupryniak L, Strzelczyk J, Pawlowski M, et al. Mild elevation of fasting plasma glucose is a strong risk factor for postoperative complications in gastric bypass patients. Obes Surg. 2004;14(10):1393-7.
    Czupryniak, L., Strzelczyk, J., Pawlowski, M., & Loba, J. (2004). Mild elevation of fasting plasma glucose is a strong risk factor for postoperative complications in gastric bypass patients. Obesity Surgery, 14(10), pp. 1393-7.
    Czupryniak L, et al. Mild Elevation of Fasting Plasma Glucose Is a Strong Risk Factor for Postoperative Complications in Gastric Bypass Patients. Obes Surg. 2004;14(10):1393-7. PubMed PMID: 15603657.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Mild elevation of fasting plasma glucose is a strong risk factor for postoperative complications in gastric bypass patients. AU - Czupryniak,Leszek, AU - Strzelczyk,Janusz, AU - Pawlowski,Maciej, AU - Loba,Jerzy, PY - 2004/12/18/pubmed PY - 2005/3/23/medline PY - 2004/12/18/entrez SP - 1393 EP - 7 JF - Obesity surgery JO - Obes Surg VL - 14 IS - 10 N2 - BACKGROUND: Bariatric surgery may be associated with surgical complications. The aim of the study was to identify significant risk factors for postoperative complications in patients undergoing Roux-en-Y gastric bypass (RYGBP). METHODS: The study consisted of 75 consecutive patients undergoing RYGBP. Full medical examination was performed, and the following parameters were assessed in the fasting state: plasma glucose, insulin, leptin, serum lipids, liver function tests, and lipoprotein Lp(a). All subjects had oral 75 g glucose tolerance test before the surgery. All complications occurring within 6 months after the RYGBP were recorded. The patients were divided into Group 1 - patients in whom complications occurred, and Group 2 - patients with no complications in the 6-month period. RESULTS: Postoperative complications occurred in 16 patients (wound infection, hernia, splenic injury, gastro-jejunal obstruction, duodenal ulcer, lower limb deep vein thrombosis). 3 significant risk factors for postoperative complications within 6 months after gastric bypass were found: 1) fasting plasma glucose >/= 6.0 mmol/l (OR 11.0; 95% confidence interval (CI) 2.1-77.3), 2) age >/=40 years (OR 5.89, 95% CI 1.35-29.4), and 3) BMI >/=45 kg/m(2) (OR 4.1, 95% CI 1.04-17.2). CONCLUSION: RYGBP is associated with increased risk of developing early postoperative complications in subjects with even slightly elevated fasting plasma glucose, age >/=40 and BMI >/=45 kg/m(2). SN - 0960-8923 UR - https://www.unboundmedicine.com/medline/citation/15603657/Mild_elevation_of_fasting_plasma_glucose_is_a_strong_risk_factor_for_postoperative_complications_in_gastric_bypass_patients_ L2 - https://dx.doi.org/10.1381/0960892042583761 DB - PRIME DP - Unbound Medicine ER -