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The role of epidemiology in the introduction of vi polysaccharide typhoid fever vaccines in Asia.
J Health Popul Nutr. 2004 Sep; 22(3):240-5.JH

Abstract

Despite the availability of at least two licensed typhoid fever vaccines--injectable sub-unit Vi polysaccharide vaccine and live, oral Ty21a vaccine--for the last decade, these vaccines have not been widely introduced in public-health programmes in countries endemic for typhoid fever. The goal of the multidisciplinary DOMI (Diseases of the Most Impoverished) typhoid fever programme is to generate policy-relevant data to support public decision-making regarding the introduction of Vi polysaccharide typhoid fever immunization programmes in China, Viet Nam, Pakistan, India, Bangladesh, and Indonesia. Through epidemiological studies, the DOMI Programme is generating these data and is offering a model for the accelerated, rational introduction of new vaccines into health programmes in low-income countries. Practical and specific examples of the role of epidemiology are described in this paper. These examples cover: (a) selection of available typhoid fever vaccines to be introduced in the programme, (b) generation of policy-relevant data, (c) providing the 'backbone' for the implementation of other multidisciplinary projects, and (d) generation of unexpected but useful information relevant for the introduction of vaccines. Epidemiological studies contribute to all stages of development of vaccine evaluation and introduction.

Authors+Show Affiliations

Acosta CJ
International Vaccine Institute, Seoul, Republic of Korea. Camilo_acosta2003@yahoo.com
Galindo CM
No affiliation info available
Ochiai RL
No affiliation info available
Danovaro-Holliday MC
No affiliation info available
Page AL
No affiliation info available
Thiem VD
No affiliation info available
Park JK
No affiliation info available
Park E
No affiliation info available
Koo H
No affiliation info available
Wang XY
No affiliation info available
Abu-Elyazeed R
No affiliation info available
Ali M
No affiliation info available
Albert MJ
No affiliation info available
Ivanoff B
No affiliation info available
Pang T
No affiliation info available
Xu ZY
No affiliation info available
Clemens JD
No affiliation info available

MeSH

AsiaBacterial VaccinesCost of IllnessDeveloping CountriesEpidemiologic StudiesHumansImmunization ProgramsPolysaccharides, BacterialSalmonella typhiTyphoid FeverTyphoid-Paratyphoid VaccinesVaccines, AttenuatedVaccines, Inactivated

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15609776

Clinical Trial Links

Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central Vietnam
Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever
Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, China
Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood

Citation

Acosta, Camilo J., et al. "The Role of Epidemiology in the Introduction of Vi Polysaccharide Typhoid Fever Vaccines in Asia." Journal of Health, Population, and Nutrition, vol. 22, no. 3, 2004, pp. 240-5.
Acosta CJ, Galindo CM, Ochiai RL, et al. The role of epidemiology in the introduction of vi polysaccharide typhoid fever vaccines in Asia. J Health Popul Nutr. 2004;22(3):240-5.
Acosta, C. J., Galindo, C. M., Ochiai, R. L., Danovaro-Holliday, M. C., Page, A. L., Thiem, V. D., Park, J. K., Park, E., Koo, H., Wang, X. Y., Abu-Elyazeed, R., Ali, M., Albert, M. J., Ivanoff, B., Pang, T., Xu, Z. Y., & Clemens, J. D. (2004). The role of epidemiology in the introduction of vi polysaccharide typhoid fever vaccines in Asia. Journal of Health, Population, and Nutrition, 22(3), 240-5.
Acosta CJ, et al. The Role of Epidemiology in the Introduction of Vi Polysaccharide Typhoid Fever Vaccines in Asia. J Health Popul Nutr. 2004;22(3):240-5. PubMed PMID: 15609776.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of epidemiology in the introduction of vi polysaccharide typhoid fever vaccines in Asia. AU - Acosta,Camilo J, AU - Galindo,Claudia M, AU - Ochiai,R Leon, AU - Danovaro-Holliday,M Carolina, AU - Page,Anne-Laure, AU - Thiem,Vu Dinh, AU - Park,Jin Kyoung, AU - Park,Eunsik, AU - Koo,Hyewon, AU - Wang,Xuan-Yi, AU - Abu-Elyazeed,Remon, AU - Ali,Mohammad, AU - Albert,M John, AU - Ivanoff,Bernard, AU - Pang,Tikki, AU - Xu,Zhi-Yi, AU - Clemens,John D, PY - 2004/12/22/pubmed PY - 2005/5/6/medline PY - 2004/12/22/entrez SP - 240 EP - 5 JF - Journal of health, population, and nutrition JO - J Health Popul Nutr VL - 22 IS - 3 N2 - Despite the availability of at least two licensed typhoid fever vaccines--injectable sub-unit Vi polysaccharide vaccine and live, oral Ty21a vaccine--for the last decade, these vaccines have not been widely introduced in public-health programmes in countries endemic for typhoid fever. The goal of the multidisciplinary DOMI (Diseases of the Most Impoverished) typhoid fever programme is to generate policy-relevant data to support public decision-making regarding the introduction of Vi polysaccharide typhoid fever immunization programmes in China, Viet Nam, Pakistan, India, Bangladesh, and Indonesia. Through epidemiological studies, the DOMI Programme is generating these data and is offering a model for the accelerated, rational introduction of new vaccines into health programmes in low-income countries. Practical and specific examples of the role of epidemiology are described in this paper. These examples cover: (a) selection of available typhoid fever vaccines to be introduced in the programme, (b) generation of policy-relevant data, (c) providing the 'backbone' for the implementation of other multidisciplinary projects, and (d) generation of unexpected but useful information relevant for the introduction of vaccines. Epidemiological studies contribute to all stages of development of vaccine evaluation and introduction. SN - 1606-0997 UR - https://www.unboundmedicine.com/medline/citation/15609776/The_role_of_epidemiology_in_the_introduction_of_vi_polysaccharide_typhoid_fever_vaccines_in_Asia_ DB - PRIME DP - Unbound Medicine ER -