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[Influence of live flora on lactose digestion in male adult lactose-malabsorbers after dairy products intake].
Wei Sheng Yan Jiu. 2004 Sep; 33(5):603-5.WS

Abstract

OBJECTIVE

To evaluate the effect of live flora on lactose absorption in male adult lactose-malabsorbers.

METHODS

After giving consents, 45 health male adult volunteers were challenged with 20 g lactose in 200 ml water in the morning without breakfast. The expired samples of breath were collected at every 30 min point in 3 hours. 24 persons were chosen as subjects (lactose-malabsorbers) when their expired H2 of any time point was 30 micromol/mol more than the baseline, and divided into 3 groups randomly. The test dairy were yogurt (Y) and heat-treated yogurt (HY), and acidified gelled milk (M), all containing 20 g lactose. The study was double blind, randomized and 3 x 3 latin square design. Three group subjects ingested the 3 different dairy products in 3 different days. The washout time was 7 days. After drinking each dairy in the morning without breakfast, the expired samples at every 30 min were collected during 8 hours test time with no food and no violent exercise. Hydrogen concentration of expired sample was detected by gas chromatography.

RESULTS

The peak hydrogen concentration (Cmax) of yogurt is significant less than heat-treated yogurt and milk (Y 113.2 +/- 70.2, HY 186.5 +/- 96.7, M 174.7 +/- 73.9). The peak time of Cmax (Tmax) of yogurt is significant more than milk (Y 390 +/- 86, M 305 +/- 105). The area under the hydrogen concentration curve (AUC) of yogurt is significant less than the other two dairy products (Y 14,900.1 +/- 12,206.2, HY 27,389.5 +/- 20,429.8, M 25,648.2 +/- 14,064.0).

CONCLUSION

The live flora in dairy product could improve lactose digestion in male adult lactose malabsorbers.

Authors+Show Affiliations

He M
Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Antoine JM
No affiliation info available
Yang Y
No affiliation info available
Yang J
No affiliation info available
Men J
No affiliation info available
Han H
No affiliation info available

MeSH

AdultAnimalsArea Under CurveDouble-Blind MethodHumansHydrogenLactobacillusLactoseLactose IntoleranceMaleMilkStreptococcus thermophilusYogurt

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15612492

Citation

He, Mei, et al. "[Influence of Live Flora On Lactose Digestion in Male Adult Lactose-malabsorbers After Dairy Products Intake]." Wei Sheng Yan Jiu = Journal of Hygiene Research, vol. 33, no. 5, 2004, pp. 603-5.
He M, Antoine JM, Yang Y, et al. [Influence of live flora on lactose digestion in male adult lactose-malabsorbers after dairy products intake]. Wei Sheng Yan Jiu. 2004;33(5):603-5.
He, M., Antoine, J. M., Yang, Y., Yang, J., Men, J., & Han, H. (2004). [Influence of live flora on lactose digestion in male adult lactose-malabsorbers after dairy products intake]. Wei Sheng Yan Jiu = Journal of Hygiene Research, 33(5), 603-5.
He M, et al. [Influence of Live Flora On Lactose Digestion in Male Adult Lactose-malabsorbers After Dairy Products Intake]. Wei Sheng Yan Jiu. 2004;33(5):603-5. PubMed PMID: 15612492.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Influence of live flora on lactose digestion in male adult lactose-malabsorbers after dairy products intake]. AU - He,Mei, AU - Antoine,Jean-Mechile, AU - Yang,Yuexin, AU - Yang,Jingming, AU - Men,Jianhua, AU - Han,Hui, PY - 2004/12/23/pubmed PY - 2006/10/7/medline PY - 2004/12/23/entrez SP - 603 EP - 5 JF - Wei sheng yan jiu = Journal of hygiene research JO - Wei Sheng Yan Jiu VL - 33 IS - 5 N2 - OBJECTIVE: To evaluate the effect of live flora on lactose absorption in male adult lactose-malabsorbers. METHODS: After giving consents, 45 health male adult volunteers were challenged with 20 g lactose in 200 ml water in the morning without breakfast. The expired samples of breath were collected at every 30 min point in 3 hours. 24 persons were chosen as subjects (lactose-malabsorbers) when their expired H2 of any time point was 30 micromol/mol more than the baseline, and divided into 3 groups randomly. The test dairy were yogurt (Y) and heat-treated yogurt (HY), and acidified gelled milk (M), all containing 20 g lactose. The study was double blind, randomized and 3 x 3 latin square design. Three group subjects ingested the 3 different dairy products in 3 different days. The washout time was 7 days. After drinking each dairy in the morning without breakfast, the expired samples at every 30 min were collected during 8 hours test time with no food and no violent exercise. Hydrogen concentration of expired sample was detected by gas chromatography. RESULTS: The peak hydrogen concentration (Cmax) of yogurt is significant less than heat-treated yogurt and milk (Y 113.2 +/- 70.2, HY 186.5 +/- 96.7, M 174.7 +/- 73.9). The peak time of Cmax (Tmax) of yogurt is significant more than milk (Y 390 +/- 86, M 305 +/- 105). The area under the hydrogen concentration curve (AUC) of yogurt is significant less than the other two dairy products (Y 14,900.1 +/- 12,206.2, HY 27,389.5 +/- 20,429.8, M 25,648.2 +/- 14,064.0). CONCLUSION: The live flora in dairy product could improve lactose digestion in male adult lactose malabsorbers. SN - 1000-8020 UR - https://www.unboundmedicine.com/medline/citation/15612492/[Influence_of_live_flora_on_lactose_digestion_in_male_adult_lactose_malabsorbers_after_dairy_products_intake]_ L2 - https://medlineplus.gov/lactoseintolerance.html DB - PRIME DP - Unbound Medicine ER -