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Use of convalescent plasma therapy in SARS patients in Hong Kong.
Eur J Clin Microbiol Infect Dis. 2005 Jan; 24(1):44-6.EJ

Abstract

In order to evaluate the efficacy of convalescent plasma therapy in the treatment of patients with severe acute respiratory syndrome (SARS), 80 SARS patients were given convalescent plasma at Prince of Wales Hospital, Hong Kong, between 20 March and 26 May 2003. Good outcome was defined as discharge by day 22 following the onset of SARS symptoms. Poor outcome was defined as death or hospitalization beyond 22 days. A higher day-22 discharge rate was observed among patients who were given convalescent plasma before day 14 of illness (58.3% vs 15.6%; P<0.001) and among those who were PCR positive and seronegative for coronavirus at the time of plasma infusion (66.7% vs 20%; P=0.001).

Authors+Show Affiliations

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, Hong Kong. gcheng@cuhk.edu.hkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

15616839

Citation

Cheng, Y, et al. "Use of Convalescent Plasma Therapy in SARS Patients in Hong Kong." European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, vol. 24, no. 1, 2005, pp. 44-6.
Cheng Y, Wong R, Soo YO, et al. Use of convalescent plasma therapy in SARS patients in Hong Kong. Eur J Clin Microbiol Infect Dis. 2005;24(1):44-6.
Cheng, Y., Wong, R., Soo, Y. O., Wong, W. S., Lee, C. K., Ng, M. H., Chan, P., Wong, K. C., Leung, C. B., & Cheng, G. (2005). Use of convalescent plasma therapy in SARS patients in Hong Kong. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 24(1), 44-6.
Cheng Y, et al. Use of Convalescent Plasma Therapy in SARS Patients in Hong Kong. Eur J Clin Microbiol Infect Dis. 2005;24(1):44-6. PubMed PMID: 15616839.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of convalescent plasma therapy in SARS patients in Hong Kong. AU - Cheng,Y, AU - Wong,R, AU - Soo,Y O Y, AU - Wong,W S, AU - Lee,C K, AU - Ng,M H L, AU - Chan,P, AU - Wong,K C, AU - Leung,C B, AU - Cheng,G, PY - 2004/12/24/pubmed PY - 2005/3/11/medline PY - 2004/12/24/entrez SP - 44 EP - 6 JF - European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology JO - Eur J Clin Microbiol Infect Dis VL - 24 IS - 1 N2 - In order to evaluate the efficacy of convalescent plasma therapy in the treatment of patients with severe acute respiratory syndrome (SARS), 80 SARS patients were given convalescent plasma at Prince of Wales Hospital, Hong Kong, between 20 March and 26 May 2003. Good outcome was defined as discharge by day 22 following the onset of SARS symptoms. Poor outcome was defined as death or hospitalization beyond 22 days. A higher day-22 discharge rate was observed among patients who were given convalescent plasma before day 14 of illness (58.3% vs 15.6%; P<0.001) and among those who were PCR positive and seronegative for coronavirus at the time of plasma infusion (66.7% vs 20%; P=0.001). SN - 0934-9723 UR - https://www.unboundmedicine.com/medline/citation/15616839/full_citation L2 - https://dx.doi.org/10.1007/s10096-004-1271-9 DB - PRIME DP - Unbound Medicine ER -