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Nutritional support in acute pancreatitis.
Nutr Clin Care. 2004 Jul-Sep; 7(3):98-103.NC

Abstract

This paper reviews the current practice of nutritional support in acute pancreatitis. Appropriate interventions depend on the severity and duration of the pancreatitis and its complications. Current trends are away from restriction of oral or enteral intake, instead preferring this route to parenteral administration if possible. The role of the gut mucosal barrier in the pathogensis of the systemic response in pancreatitis has led to attempts to use enteral nutritional support to prevent complications, in addition to meeting nutritional needs in patients with long-term severe illness. Many clinicians believe that the management of acute pancreatitis should start from the concept of "pancreatic rest." Based on a simple understanding of pancreatic physiology and a belief that further stimulation of the pancreas during an attack of pancreatitis would exacerbate the inflammatory process by releasing more enzymes, traditional teaching has been that it is necessary to avoid all oral intake to prevent any inappropriate stimulation of pancreatic enzyme production. Accordingly, patients with acute pancreatitis are often deprived of enteral nutrition, and may be given intravenous parenteral nutritional support. Such an approach to nutritional support needs to be revised, since evidence emerging from many recent studies consistently indicates that an enteral route of nutrition is far superior.

Authors+Show Affiliations

School of Medicine, University of Belgrade, Serbia.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15624541

Citation

Radenkovic, Dejan, and Colin D. Johnson. "Nutritional Support in Acute Pancreatitis." Nutrition in Clinical Care : an Official Publication of Tufts University, vol. 7, no. 3, 2004, pp. 98-103.
Radenkovic D, Johnson CD. Nutritional support in acute pancreatitis. Nutr Clin Care. 2004;7(3):98-103.
Radenkovic, D., & Johnson, C. D. (2004). Nutritional support in acute pancreatitis. Nutrition in Clinical Care : an Official Publication of Tufts University, 7(3), 98-103.
Radenkovic D, Johnson CD. Nutritional Support in Acute Pancreatitis. Nutr Clin Care. 2004 Jul-Sep;7(3):98-103. PubMed PMID: 15624541.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutritional support in acute pancreatitis. AU - Radenkovic,Dejan, AU - Johnson,Colin D, PY - 2004/12/31/pubmed PY - 2005/2/3/medline PY - 2004/12/31/entrez SP - 98 EP - 103 JF - Nutrition in clinical care : an official publication of Tufts University JO - Nutr Clin Care VL - 7 IS - 3 N2 - This paper reviews the current practice of nutritional support in acute pancreatitis. Appropriate interventions depend on the severity and duration of the pancreatitis and its complications. Current trends are away from restriction of oral or enteral intake, instead preferring this route to parenteral administration if possible. The role of the gut mucosal barrier in the pathogensis of the systemic response in pancreatitis has led to attempts to use enteral nutritional support to prevent complications, in addition to meeting nutritional needs in patients with long-term severe illness. Many clinicians believe that the management of acute pancreatitis should start from the concept of "pancreatic rest." Based on a simple understanding of pancreatic physiology and a belief that further stimulation of the pancreas during an attack of pancreatitis would exacerbate the inflammatory process by releasing more enzymes, traditional teaching has been that it is necessary to avoid all oral intake to prevent any inappropriate stimulation of pancreatic enzyme production. Accordingly, patients with acute pancreatitis are often deprived of enteral nutrition, and may be given intravenous parenteral nutritional support. Such an approach to nutritional support needs to be revised, since evidence emerging from many recent studies consistently indicates that an enteral route of nutrition is far superior. SN - 1096-6781 UR - https://www.unboundmedicine.com/medline/citation/15624541/Nutritional_support_in_acute_pancreatitis_ DB - PRIME DP - Unbound Medicine ER -