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Smoking cessation and mortality from cardiovascular disease among Japanese men and women: the JACC Study.
Am J Epidemiol. 2005 Jan 15; 161(2):170-9.AJ

Abstract

To examine the effect of smoking cessation on cardiovascular disease mortality in Asians, the authors conducted a 10-year prospective cohort study of 94,683 Japanese (41,782 men and 52,901 women) aged 40-79 years who were part of the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study). During 941,043 person-years of follow-up between 1989-1990 and 1999, 698 deaths from stroke, 348 from coronary heart disease, and 1,555 from total cardiovascular disease occurred in men and 550, 199, and 1,155, respectively, in women. For men, the multivariate relative risks for current smokers compared with never smokers were 1.39 (95% confidence interval (CI): 1.13, 1.70) for stroke, 2.51 (95% CI: 1.79, 3.51) for coronary heart disease, and 1.60 (95% CI: 1.39, 1.84) for total cardiovascular disease. The respective relative risks for women were 1.65 (95% CI: 1.21, 2.25), 3.35 (95% CI: 2.23, 5.02), and 2.06 (95% CI: 1.69, 2.51), with larger excess risks for persons aged 40-64 years than for older persons. The risk decline after smoking cessation occurred for coronary heart disease and total cardiovascular disease within 2 years and for total stroke after 2-4 years. For each endpoint and in both age subgroups of 40-64 and 65-79 years, most of the benefit of cessation occurred after 10-14 years following cessation. Findings imply the importance of smoking cessation at any age to prevent cardiovascular disease in Japanese.

Authors+Show Affiliations

Iso H
Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba-shi, Ibaraki-ken 305-3585, Japan. fvgh5640@mb.infoweb.ne.jp
Date C
No affiliation info available
Yamamoto A
No affiliation info available
Toyoshima H
No affiliation info available
Watanabe Y
No affiliation info available
Kikuchi S
No affiliation info available
Koizumi A
No affiliation info available
Wada Y
No affiliation info available
Kondo T
No affiliation info available
Inaba Y
No affiliation info available
Tamakoshi A
No affiliation info available
JACC Study Group
No affiliation info available

MeSH

AdultAge DistributionAgedCardiovascular DiseasesFemaleFollow-Up StudiesHumansJapanLife StyleMaleMiddle AgedProspective StudiesRisk AssessmentSex DistributionSmokingSmoking CessationTime Factors

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15632267

Citation

Iso, Hiroyasu, et al. "Smoking Cessation and Mortality From Cardiovascular Disease Among Japanese Men and Women: the JACC Study." American Journal of Epidemiology, vol. 161, no. 2, 2005, pp. 170-9.
Iso H, Date C, Yamamoto A, et al. Smoking cessation and mortality from cardiovascular disease among Japanese men and women: the JACC Study. Am J Epidemiol. 2005;161(2):170-9.
Iso, H., Date, C., Yamamoto, A., Toyoshima, H., Watanabe, Y., Kikuchi, S., Koizumi, A., Wada, Y., Kondo, T., Inaba, Y., & Tamakoshi, A. (2005). Smoking cessation and mortality from cardiovascular disease among Japanese men and women: the JACC Study. American Journal of Epidemiology, 161(2), 170-9.
Iso H, et al. Smoking Cessation and Mortality From Cardiovascular Disease Among Japanese Men and Women: the JACC Study. Am J Epidemiol. 2005 Jan 15;161(2):170-9. PubMed PMID: 15632267.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Smoking cessation and mortality from cardiovascular disease among Japanese men and women: the JACC Study. AU - Iso,Hiroyasu, AU - Date,Chigusa, AU - Yamamoto,Akio, AU - Toyoshima,Hideaki, AU - Watanabe,Yoshiyuki, AU - Kikuchi,Shogo, AU - Koizumi,Akio, AU - Wada,Yasuhiko, AU - Kondo,Takaaki, AU - Inaba,Yutaka, AU - Tamakoshi,Akiko, AU - ,, PY - 2005/1/6/pubmed PY - 2005/2/26/medline PY - 2005/1/6/entrez SP - 170 EP - 9 JF - American journal of epidemiology JO - Am J Epidemiol VL - 161 IS - 2 N2 - To examine the effect of smoking cessation on cardiovascular disease mortality in Asians, the authors conducted a 10-year prospective cohort study of 94,683 Japanese (41,782 men and 52,901 women) aged 40-79 years who were part of the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study). During 941,043 person-years of follow-up between 1989-1990 and 1999, 698 deaths from stroke, 348 from coronary heart disease, and 1,555 from total cardiovascular disease occurred in men and 550, 199, and 1,155, respectively, in women. For men, the multivariate relative risks for current smokers compared with never smokers were 1.39 (95% confidence interval (CI): 1.13, 1.70) for stroke, 2.51 (95% CI: 1.79, 3.51) for coronary heart disease, and 1.60 (95% CI: 1.39, 1.84) for total cardiovascular disease. The respective relative risks for women were 1.65 (95% CI: 1.21, 2.25), 3.35 (95% CI: 2.23, 5.02), and 2.06 (95% CI: 1.69, 2.51), with larger excess risks for persons aged 40-64 years than for older persons. The risk decline after smoking cessation occurred for coronary heart disease and total cardiovascular disease within 2 years and for total stroke after 2-4 years. For each endpoint and in both age subgroups of 40-64 and 65-79 years, most of the benefit of cessation occurred after 10-14 years following cessation. Findings imply the importance of smoking cessation at any age to prevent cardiovascular disease in Japanese. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/15632267/Smoking_cessation_and_mortality_from_cardiovascular_disease_among_Japanese_men_and_women:_the_JACC_Study_ DB - PRIME DP - Unbound Medicine ER -