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[The diagnostic ability of Heidelberg retina tomography to detect glaucomatous optic neuropathy in Chinese].
Zhonghua Yan Ke Za Zhi. 2004 Nov; 40(11):737-40.ZY

Abstract

OBJECTIVE

To evaluate the ability of Heidelberg retina tomography (HRT) in the diagnosis of primary open angle glaucoma (POAG).

METHODS

The topography of optic nerve head of 116 normal eyes and 99 eyes with POAG were examined using HRT. The differences of the optic disc parameters between two groups were compared. The topographic parameters of the optic nerve head were undergone stepwised discriminant analysis and the discriminant function was established. The sensitive diagnostic parameters of POAG were screened.

RESULTS

The topographic parameters of optic nerve head, including disc area (DA), cup area (CA), cup/disc area ratio (C/DAR), rim area (RA), height variation contour (HVC), cup volume (CV), rim volume (RV), mean cup depth (MCD), maximum cup depth (MxCD), cup shape measure (CSM), mean retinal nerve fiber layer thickness (mRNFLT), retinal nerve fiber layer cross section area (RNFLA), showed significant (P < 0.001) difference between normal subjects and patients with POAG. The sensitive diagnostic parameters of POAG were C/DAR, RA, CSM, CV, MCD. The discriminant function was Y = -2.083-4.833 x C/DAR-20.379 x CSM + 2.035 x RA + 3.955 x CV-3.701 x MxCD. The sensitivity, specificity and diagnostic accuracy were 81.8%, 86.2% and 84.2%, respectively, which were comparable to the automatic analysis program of HRT.

CONCLUSIONS

The topographic parameters of optic nerve head in patients with POAG showed significant differences from that in normal people. The power of discriminant function established based on our data was comparable to the HRT automatic analysis program. Our results indicate that HRT automatic analysis program is applicable to Chinese.

Authors+Show Affiliations

Zhongshan Ophthalmic Center, Zhongshan University, Guangzhou 510060, China. ykoct@gzsums.edu.cnNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15634479

Citation

Liu, Xing, et al. "[The Diagnostic Ability of Heidelberg Retina Tomography to Detect Glaucomatous Optic Neuropathy in Chinese]." [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, vol. 40, no. 11, 2004, pp. 737-40.
Liu X, Liang YB, Ling YL, et al. [The diagnostic ability of Heidelberg retina tomography to detect glaucomatous optic neuropathy in Chinese]. Zhonghua Yan Ke Za Zhi. 2004;40(11):737-40.
Liu, X., Liang, Y. B., Ling, Y. L., Huang, J. J., & Zheng, X. P. (2004). [The diagnostic ability of Heidelberg retina tomography to detect glaucomatous optic neuropathy in Chinese]. [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, 40(11), 737-40.
Liu X, et al. [The Diagnostic Ability of Heidelberg Retina Tomography to Detect Glaucomatous Optic Neuropathy in Chinese]. Zhonghua Yan Ke Za Zhi. 2004;40(11):737-40. PubMed PMID: 15634479.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The diagnostic ability of Heidelberg retina tomography to detect glaucomatous optic neuropathy in Chinese]. AU - Liu,Xing, AU - Liang,Yuan-Bo, AU - Ling,Yun-Lan, AU - Huang,Jing-Jing, AU - Zheng,Xiao-Ping, PY - 2005/1/7/pubmed PY - 2006/12/15/medline PY - 2005/1/7/entrez SP - 737 EP - 40 JF - [Zhonghua yan ke za zhi] Chinese journal of ophthalmology JO - Zhonghua Yan Ke Za Zhi VL - 40 IS - 11 N2 - OBJECTIVE: To evaluate the ability of Heidelberg retina tomography (HRT) in the diagnosis of primary open angle glaucoma (POAG). METHODS: The topography of optic nerve head of 116 normal eyes and 99 eyes with POAG were examined using HRT. The differences of the optic disc parameters between two groups were compared. The topographic parameters of the optic nerve head were undergone stepwised discriminant analysis and the discriminant function was established. The sensitive diagnostic parameters of POAG were screened. RESULTS: The topographic parameters of optic nerve head, including disc area (DA), cup area (CA), cup/disc area ratio (C/DAR), rim area (RA), height variation contour (HVC), cup volume (CV), rim volume (RV), mean cup depth (MCD), maximum cup depth (MxCD), cup shape measure (CSM), mean retinal nerve fiber layer thickness (mRNFLT), retinal nerve fiber layer cross section area (RNFLA), showed significant (P < 0.001) difference between normal subjects and patients with POAG. The sensitive diagnostic parameters of POAG were C/DAR, RA, CSM, CV, MCD. The discriminant function was Y = -2.083-4.833 x C/DAR-20.379 x CSM + 2.035 x RA + 3.955 x CV-3.701 x MxCD. The sensitivity, specificity and diagnostic accuracy were 81.8%, 86.2% and 84.2%, respectively, which were comparable to the automatic analysis program of HRT. CONCLUSIONS: The topographic parameters of optic nerve head in patients with POAG showed significant differences from that in normal people. The power of discriminant function established based on our data was comparable to the HRT automatic analysis program. Our results indicate that HRT automatic analysis program is applicable to Chinese. SN - 0412-4081 UR - https://www.unboundmedicine.com/medline/citation/15634479/[The_diagnostic_ability_of_Heidelberg_retina_tomography_to_detect_glaucomatous_optic_neuropathy_in_Chinese]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0412-4081&amp;year=2004&amp;vol=40&amp;issue=11&amp;fpage=737 DB - PRIME DP - Unbound Medicine ER -