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Declining hepatitis A seroprevalence: a global review and analysis.
Epidemiol Infect. 2004 Dec; 132(6):1005-22.EI

Abstract

Hepatitis A virus (HAV) is spread by faecal-oral contact or ingestion of contaminated food or water. Lifelong immunity is conferred by infection or vaccination, so anti-HAV seroprevalence studies can be used to indicate which populations are susceptible to infection. Seroprevalence rates are highly correlated with socioeconomic status and access to clean water and sanitation. Increasing household income, education, water quality and quantity, sanitation, and hygiene leads to decreases in HAV prevalence. Japan, Australia, New Zealand, Canada, the United States, and most European nations have low anti-HAV rates. Although anti-HAV rates remain high in most Latin American, Asian, and Middle Eastern nations, average seroprevalence rates are declining. Surveys from Africa generally indicate no significant decline in anti-HAV rates. Because the severity of illness increases with age, populations with a high proportion of susceptible adults should consider targeted vaccination programmes.

Authors+Show Affiliations

Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15635957

Citation

Jacobsen, K H., and J S. Koopman. "Declining Hepatitis a Seroprevalence: a Global Review and Analysis." Epidemiology and Infection, vol. 132, no. 6, 2004, pp. 1005-22.
Jacobsen KH, Koopman JS. Declining hepatitis A seroprevalence: a global review and analysis. Epidemiol Infect. 2004;132(6):1005-22.
Jacobsen, K. H., & Koopman, J. S. (2004). Declining hepatitis A seroprevalence: a global review and analysis. Epidemiology and Infection, 132(6), 1005-22.
Jacobsen KH, Koopman JS. Declining Hepatitis a Seroprevalence: a Global Review and Analysis. Epidemiol Infect. 2004;132(6):1005-22. PubMed PMID: 15635957.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Declining hepatitis A seroprevalence: a global review and analysis. AU - Jacobsen,K H, AU - Koopman,J S, PY - 2005/1/8/pubmed PY - 2005/1/27/medline PY - 2005/1/8/entrez SP - 1005 EP - 22 JF - Epidemiology and infection JO - Epidemiol. Infect. VL - 132 IS - 6 N2 - Hepatitis A virus (HAV) is spread by faecal-oral contact or ingestion of contaminated food or water. Lifelong immunity is conferred by infection or vaccination, so anti-HAV seroprevalence studies can be used to indicate which populations are susceptible to infection. Seroprevalence rates are highly correlated with socioeconomic status and access to clean water and sanitation. Increasing household income, education, water quality and quantity, sanitation, and hygiene leads to decreases in HAV prevalence. Japan, Australia, New Zealand, Canada, the United States, and most European nations have low anti-HAV rates. Although anti-HAV rates remain high in most Latin American, Asian, and Middle Eastern nations, average seroprevalence rates are declining. Surveys from Africa generally indicate no significant decline in anti-HAV rates. Because the severity of illness increases with age, populations with a high proportion of susceptible adults should consider targeted vaccination programmes. SN - 0950-2688 UR - https://www.unboundmedicine.com/medline/citation/15635957/Declining_hepatitis_A_seroprevalence:_a_global_review_and_analysis_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=15635957.ui DB - PRIME DP - Unbound Medicine ER -